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HomoloGene:2699. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IKBKAP,  H.sapiens
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
NP_003631.2
1332 aa
IKBKAP,  P.troglodytes
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
XP_001143066.2
1312 aa
LOC713524,  M.mulatta
elongator complex protein 1-like
XP_002808145.1
1426 aa
IKBKAP,  C.lupus
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
XP_005626959.1
1337 aa
IKBKAP,  B.taurus
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
XP_003586478.2
1203 aa
Ikbkap,  M.musculus
inhibitor of kappa light polypeptide enhancer in B cells, kinase complex-associated protein
NP_080355.2
1333 aa
Ikbkap,  R.norvegicus
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
NP_543175.1
1331 aa
IKBKAP,  G.gallus
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
XP_003643119.1
1334 aa
ikbkap,  X.tropicalis
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
NP_001123686.1
1249 aa
ikbkap,  D.rerio
inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complex-associated protein
XP_689534.5
1311 aa
Elp1,  D.melanogaster
Elongator complex protein 1
NP_001262478.1
1256 aa
AgaP_AGAP003979,  A.gambiae
AgaP_AGAP003979
XP_318429.4
1326 aa
IKI3,  S.cerevisiae
IKI3
NP_013488.3
1349 aa
KLLA0E05237g,  K.lactis
KLLA0E05237g
XP_454181.1
1325 aa
AGOS_AER047C,  E.gossypii
AGOS_AER047C
NP_984907.2
1324 aa
iki3,  S.pombe
iki3
NP_595335.1
1253 aa
MGG_07174,  M.oryzae
MGG_07174
XP_003715376.1
1305 aa
NCU01486,  N.crassa
NCU01486
XP_956763.1
1342 aa
ABO1,  A.thaliana
ABO1
NP_196872.1
1319 aa
Os07g0563700,  O.sativa
Os07g0563700
NP_001059998.1
1343 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Dysautonomia, familial.



Publications
Articles associated with genes and sequences of this homology group.

Afferent baroreflex failure in familial dysautonomia.
Norcliffe-Kaufmann L, et al. Neurology 75, 1904-11 (2010).
Familial Dysautonomia
Shohat M, et al. (1993).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
IKI3 (pfam04762)
  IKI3 family.
NrfG (COG0457)
  FOG: TPR repeat [General function prediction only].
COG5290 (COG5290)
  IkappaB kinase complex, IKAP component [Transcription].
IKI3 (pfam04762)
  IKI3 family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ikbkap includes H.sapiens IKBKAP and R.norvegicus Ikbkap.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (20 transcripts, 14 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Aves - birds (4 transcripts, 1 species)
Ascidiacea - tunicates (3 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 3 species)
Arachnida - arachnids (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (2 transcripts, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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