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HomoloGene:994. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CNGA3,  H.sapiens
cyclic nucleotide gated channel alpha 3
NP_001289.1
694 aa
CNGA3,  P.troglodytes
cyclic nucleotide gated channel alpha 3
XP_001156943.1
694 aa
CNGA3,  M.mulatta
cyclic nucleotide gated channel alpha 3
XP_001101944.2
694 aa
CNGA3,  C.lupus
cyclic nucleotide gated channel alpha 3
XP_538462.3
708 aa
CNGA3,  B.taurus
cyclic nucleotide gated channel alpha 3
NP_776704.1
706 aa
Cnga3,  M.musculus
cyclic nucleotide gated channel alpha 3
NP_001268939.1
669 aa
Cnga3,  R.norvegicus
cyclic nucleotide gated channel alpha 3
NP_445947.1
611 aa
CNGA3,  G.gallus
cyclic nucleotide gated channel alpha 3
NP_990552.1
735 aa
LOC100494840,  X.tropicalis
cyclic nucleotide-gated channel cone photoreceptor subunit alpha-like
XP_002931690.2
737 aa
cnga3a,  D.rerio
cyclic nucleotide gated channel alpha 3a
XP_005166141.1
765 aa
Cng,  D.melanogaster
Cyclic-nucleotide-gated ion channel protein
NP_477116.1
665 aa
AgaP_AGAP009050,  A.gambiae
AgaP_AGAP009050
XP_319802.4
611 aa
tax-4,  C.elegans
tax-4
NP_499033.1
733 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Achromatopsia-2.



Publications
Articles associated with genes and sequences of this homology group.

Altered synaptic plasticity and behavioral abnormalities in CNGA3-deficient mice.
Michalakis S, et al. Genes Brain Behav 10, 137-48 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ion_trans (pfam00520)
  Ion transport protein.
Ion_trans (pfam00520)
  Ion transport protein.
CAP_ED (cl00047)
  effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
Prefoldin (cl09111)
  Prefoldin is a hexameric molecular chaperone complex, found in both eukaryotes and archaea, that binds and stabilizes newly synthesized polypeptides allowing them to fold correctly. The complex contains two alpha and four beta subunits, the two subunits ...
DRE_TIM_metallolyase (cl18962)
  DRE-TIM metallolyase superfamily.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cnga3 includes H.sapiens CNGA3 and R.norvegicus Cnga3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 7 species)
Actinopterygii - bony fishes (6 transcripts, 4 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (3 transcripts, 2 species)
Arachnida - arachnids (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

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