Display Settings:

Format

Send to:

Choose Destination

Links from OMIM

HomoloGene:41088. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ABHD5,  H.sapiens
abhydrolase domain containing 5
NP_057090.2
349 aa
ABHD5,  P.troglodytes
abhydrolase domain containing 5
XP_516397.2
349 aa
ABHD5,  M.mulatta
abhydrolase domain containing 5
XP_001107786.2
349 aa
LOC485570,  C.lupus
1-acylglycerol-3-phosphate O-acyltransferase ABHD5-like
XP_542689.2
349 aa
ABHD5,  B.taurus
abhydrolase domain containing 5
NP_001069531.1
348 aa
Abhd5,  M.musculus
abhydrolase domain containing 5
NP_080455.1
351 aa
Abhd5,  R.norvegicus
abhydrolase domain containing 5
NP_997689.1
351 aa
ABHD5,  G.gallus
abhydrolase domain containing 5
NP_001265074.1
369 aa
abhd5,  X.tropicalis
abhydrolase domain containing 5
NP_001016889.1
371 aa
abhd5a,  D.rerio
abhydrolase domain containing 5a
XP_003200181.1
344 aa
CELE_C25A1.12,  C.elegans
CELE_C25A1.12
NP_492685.2
360 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Chanarin-Dorfman syndrome.



Publications
Articles associated with genes and sequences of this homology group.

Steatohepatitis and liver cirrhosis in Chanarin-Dorfman syndrome with a new ABDH5 mutation.
Cakmak E, et al. Clin Res Hepatol Gastroenterol 36, e34-7 (2012).
Identification of a novel splicing isoform of murine CGI-58.
Yang X, et al. FEBS Lett 584, 903-10 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Esterase_lipase (cl12031)
  Esterases and lipases (includes fungal lipases, cholinesterases, etc.) These enzymes act on carboxylic esters (EC: 3.1.1.-). The catalytic apparatus involves three residues (catalytic triad): a serine, a glutamate or aspartate and a histidine.These ...
PLN02894 (PLN02894)
  hydrolase, alpha/beta fold family protein.
RGM_C (pfam06534)
  Repulsive guidance molecule (RGM) C-terminus.
MhpC (COG0596)
  Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].
Esterase_713_like (cl17303)
  Novel bacterial esterase that cleaves esters on halogenated cyclic compounds.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Abhd5 includes H.sapiens ABHD5 and R.norvegicus Abhd5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (9 transcripts, 7 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

Support Center