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HomoloGene:56683. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

CUL7,  H.sapiens
cullin 7
NP_001161842.1
1782 aa
CUL7,  P.troglodytes
cullin 7
XP_003311343.1
1782 aa
CUL7,  M.mulatta
cullin 7
XP_002803791.1
1780 aa
CUL7,  C.lupus
cullin 7
XP_538928.3
1689 aa
CUL7,  B.taurus
cullin 7
XP_005223608.1
1701 aa
Cul7,  M.musculus
cullin 7
NP_079887.3
1689 aa
LOC680835,  R.norvegicus
similar to cullin 7
XP_006244636.1
1711 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
3-M syndrome.



Publications
Articles associated with genes and sequences of this homology group.

The 3M syndrome.
Huber C, et al. Best Pract Res Clin Endocrinol Metab 25, 143-51 (2011).
A large-scale mutation search reveals genetic heterogeneity in 3M syndrome.
Huber C, et al. Eur J Hum Genet 17, 395-400 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Cul7 (pfam11515)
  Mouse development and cellular proliferation protein Cullin-7.
Cullin (pfam00888)
  Cullin family.
APC10-like (cl02148)
  APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination.
Cullin_Nedd8 (cl11186)
  Cullin protein neddylation domain.
Cullin (pfam00888)
  Cullin family.
APC10-like (cl02148)
  APC10-like DOC1 domains in E3 ubiquitin ligases that mediate substrate ubiquitination.
Cullin_Nedd8 (cl11186)
  Cullin protein neddylation domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cul7 includes H.sapiens CUL7 and R.norvegicus LOC680835.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)

 

 

 

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