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HomoloGene:45441. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ABCA12,  H.sapiens
ATP-binding cassette, sub-family A (ABC1), member 12
NP_775099.2
2595 aa
ABCA12,  P.troglodytes
ATP-binding cassette, sub-family A (ABC1), member 12
XP_001149722.1
2603 aa
ABCA12,  M.mulatta
ATP-binding cassette, sub-family A (ABC1), member 12
XP_001084970.2
2581 aa
ABCA12,  C.lupus
ATP-binding cassette, sub-family A (ABC1), member 12
XP_536058.2
2594 aa
ABCA12,  B.taurus
ATP-binding cassette, sub-family A (ABC1), member 12
NP_001178223.2
2593 aa
Abca12,  M.musculus
ATP-binding cassette, sub-family A (ABC1), member 12
NP_780419.2
2595 aa
Abca12,  R.norvegicus
ATP-binding cassette, subfamily A (ABC1), member 12
XP_237242.6
2595 aa
ABCA12,  G.gallus
ATP-binding cassette, sub-family A (ABC1), member 12
XP_421867.4
3784 aa
LOC101731410,  X.tropicalis
uncharacterized LOC101731410
XP_004918316.1
7277 aa
abca12,  X.tropicalis
ATP-binding cassette, sub-family A (ABC1), member 12
XP_004918315.1
4029 aa
abca12,  D.rerio
ATP-binding cassette, sub-family A (ABC1), member 12
XP_686632.6
5913 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Ichthyosis, harlequin.
Ichthyosis, lamellar 2.



Publications
Articles associated with genes and sequences of this homology group.

Harlequin ichthyosis in two siblings.
Habib A, et al. J Coll Physicians Surg Pak 21, 503-5 (2011).
Detection of filaggrin gene mutation (2282del4) in Pakistani Ichthyosis vulgaris families.
Naz N & Samdani AJ. J Coll Physicians Surg Pak 21, 382-3 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ABC2_membrane_3 (pfam12698)
  ABC-2 family transporter protein.
ABC2_membrane_3 (pfam12698)
  ABC-2 family transporter protein.
ABC_ATPase (cl17201)
  ATP-binding cassette transporter nucleotide-binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Abca12 includes H.sapiens ABCA12 and R.norvegicus Abca12.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Actinopterygii - bony fishes (6 transcripts, 5 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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