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HomoloGene:37856. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RIPK2,  H.sapiens
receptor-interacting serine-threonine kinase 2
NP_003812.1
540 aa
RIPK2,  P.troglodytes
receptor-interacting serine-threonine kinase 2
XP_519850.2
539 aa
RIPK2,  M.mulatta
receptor-interacting serine-threonine kinase 2
XP_001084687.1
540 aa
RIPK2,  C.lupus
receptor-interacting serine-threonine kinase 2
XP_005638158.1
538 aa
RIPK2,  B.taurus
receptor-interacting serine-threonine kinase 2
NP_001029782.1
540 aa
Ripk2,  M.musculus
receptor (TNFRSF)-interacting serine-threonine kinase 2
NP_620402.1
539 aa
Ripk2,  R.norvegicus
receptor-interacting serine-threonine kinase 2
NP_001178794.1
539 aa
RIPK2,  G.gallus
receptor-interacting serine-threonine kinase 2
NP_001026114.1
574 aa
ripk2,  X.tropicalis
receptor-interacting serine-threonine kinase 2
XP_002939201.2
553 aa
ripk2,  D.rerio
receptor-interacting serine-threonine kinase 2
NP_919392.2
584 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

RIP2 polymorphisms in inflammatory bowel diseases.
ThiƩbaut R, et al. Inflamm Bowel Dis 17, 1055 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
STYKc (smart00221)
  Protein kinase; unclassified specificity.
S_TKc (smart00220)
  Serine/Threonine protein kinases, catalytic domain.
Pkinase (pfam00069)
  Protein kinase domain.
DD_superfamily (cl14633)
  The Death Domain Superfamily of protein-protein interaction domains.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.
DD (cl14633)
  Death Domain Superfamily of protein-protein interaction domains.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ripk2 includes H.sapiens RIPK2 and R.norvegicus Ripk2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 12 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Aves - birds (1 transcript, 1 species)

 

 

 

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