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HomoloGene:8084. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PLA2G2F,  H.sapiens
phospholipase A2, group IIF
NP_073730.3
211 aa
PLA2G2F,  P.troglodytes
phospholipase A2, group IIF
XP_001163707.1
211 aa
PLA2G2F,  C.lupus
phospholipase A2, group IIF
XP_544523.2
210 aa
PLA2G2F,  B.taurus
phospholipase A2, group IIF
NP_001095992.1
196 aa
Pla2g2f,  M.musculus
phospholipase A2, group IIF
NP_036175.2
210 aa
Pla2g2f,  R.norvegicus
phospholipase A2, group IIF
NP_001103057.1
210 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Unique membrane interaction mode of group IIF phospholipase A2.
Wijewickrama GT, et al. J Biol Chem 281, 32741-54 (2006).
Cloning and recombinant expression of human group IIF-secreted phospholipase A(2).
Valentin E, et al. Biochem Biophys Res Commun 279, 223-8 (2000).
HIV and SIV envelope glycoproteins induce phospholipase A2 activation in human and macaque lymphocytes.
Mavoungou E, et al. J Acquir Immune Defic Syndr Hum Retrovirol 16, 1-9 (1997).
Mechanisms of prionSc- and HIV-1 gp120 induced neuronal cell death.
Schröder HC, et al. Neurotoxicology 19, 683-8 (1998).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PLA2_like (cl05417)
  PLA2_like: Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pla2g2f includes H.sapiens PLA2G2F and R.norvegicus Pla2g2f.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (4 transcripts, 4 species)

 

 

 

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