HomoloGene - NCBI

Warning: The NCBI web site requires JavaScript to function. more...

Links from Gene

HomoloGene:55628. Gene conserved in Euteleostomi

Download , Links

Genes Genes identified as putative homologs of one another during the construction of HomoloGene.			Proteins Proteins used in sequence comparisons and their conserved domain architectures.
	GNB3, H.sapiens guanine nucleotide binding protein (G protein), beta polypeptide 3			NP_002066.1 340 aa
	GNB3, P.troglodytes guanine nucleotide binding protein (G protein), beta polypeptide 3			XP_003313511.1 340 aa
	GNB3, M.mulatta guanine nucleotide binding protein (G protein), beta polypeptide 3			XP_001110494.1 340 aa
	GNB3, C.lupus guanine nucleotide binding protein (G protein), beta polypeptide 3			NP_001003004.1 340 aa
	GNB3, B.taurus guanine nucleotide binding protein (G protein), beta polypeptide 3			NP_001179276.1 340 aa
	Gnb3, M.musculus guanine nucleotide binding protein (G protein), beta 3			NP_038558.1 340 aa
	Gnb3, R.norvegicus guanine nucleotide binding protein (G protein), beta polypeptide 3			NP_068630.1 340 aa
	GNB3, G.gallus guanine nucleotide binding protein (G protein), beta polypeptide 3			XP_004938175.1 340 aa
	gnb3, X.tropicalis guanine nucleotide binding protein (G protein), beta polypeptide 3			NP_001011107.1 340 aa
	gnb3a, D.rerio guanine nucleotide binding protein (G protein), beta polypeptide 3a			NP_001002437.1 340 aa

Protein Alignments

Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST

Regenerate Alignments

Phenotypes Phenotypic information for the genes in this entry imported from model organism databases.
*H.sapiens*
MIM:145500 Hypertension, essential, susceptibility to.

Publications Articles associated with genes and sequences of this homology group.
The C825T polymorphism of the G-protein β3 subunit gene and its association with hypertension and stroke: an updated meta-analysis. Guo L, et al. PLoS One 8, e65863 (2013).
Cones respond to light in the absence of transducin β subunit. Nikonov SS, et al. J Neurosci 33, 5182-94 (2013).
Effect of the G-protein β3 subunit 825T allele on the change of body adiposity in obese female. Hwang IC, et al. Diabetes Obes Metab 15, 284-6 (2013).
G-protein β3 subunit gene 825C/T polymorphism and its association with the presence, severity, and duration of vasculogenic erectile dysfunction. Safarinejad MR, et al. Fertil Steril 99, 69-75.e5 (2013).
The Gβ3 splice variant associated with the C825T gene polymorphism is an unstable and functionally inactive protein. Sun Z, et al. Cell Signal 24, 2349-59 (2012).
GNB3 C825T polymorphism is associated with postural tachycardia syndrome in children. Nakao R, et al. Pediatr Int 54, 829-37 (2012).
Association between the G-protein β3 subunit C825T polymorphism with essential hypertension: a meta-analysis in Han Chinese population. Lu J, et al. Mol Biol Rep 39, 8937-44 (2012).
G Protein β3 subunit gene C825T polymorphism and its association with the presence and clinicopathological characteristics of prostate cancer. Safarinejad MR, et al. J Urol 188, 287-93 (2012).
Influence of 825 C>T polymorphism of G protein β3 subunit gene (GNB3) on hemodynamic response during dobutamine stress echocardiography. Banaś A, et al. Pharmacol Rep 64, 123-8 (2012).
The C825T GNB3 polymorphism, independent of blood pressure, predicts cerebrovascular risk at a population level. Casiglia E, et al. Am J Hypertens 25, 451-7 (2012).
See all (362)

Conserved Domains Conserved Domains from CDD found in protein sequences by rpsblast searching.
WD40 (cd00200) WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...

Related Homology Resources Links to curated and computed homology information found in other databases.
MGI:95785 Orthology group for M.musculus Gnb3 includes H.sapiens GNB3 and R.norvegicus Gnb3.

You are here: NCBI > Homology > HomoloGene