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HomoloGene:74905. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PTPN20B,  H.sapiens
protein tyrosine phosphatase, non-receptor type 20B
NP_001035816.1
420 aa
PTPN20A,  P.troglodytes
protein tyrosine phosphatase, non-receptor type 20A
XP_001136909.2
420 aa
PTPN20A,  M.mulatta
protein tyrosine phosphatase, non-receptor type 20A
XP_001109336.1
420 aa
PTPN20B,  C.lupus
protein tyrosine phosphatase, non-receptor type 20B
XP_005637522.1
418 aa
PTPN20B,  B.taurus
protein tyrosine phosphatase, non-receptor type 20B
XP_002707839.3
451 aa
Ptpn20,  M.musculus
protein tyrosine phosphatase, non-receptor type 20
NP_033004.1
426 aa
Ptpn20b,  R.norvegicus
protein tyrosine phosphatase, non-receptor type 20B
NP_001073618.1
421 aa
PTP1,  A.thaliana
PTP1
NP_001031266.1
340 aa
Os12g0174800,  O.sativa
Os12g0174800
NP_001066289.1
328 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Protein tyrosine phosphatase hPTPN20a is targeted to sites of actin polymerization.
Fodero-Tavoletti MT, et al. Biochem J 389, 343-54 (2005).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PTPc (smart00194)
  Protein tyrosine phosphatase, catalytic domain.
Y_phosphatase (pfam00102)
  Protein-tyrosine phosphatase.
PTPc (cd00047)
  Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ptpn20 includes H.sapiens PTPN20B and R.norvegicus Ptpn20.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (28 transcripts, 24 species)
Liliopsida - monocots (10 transcripts, 7 species)
Coniferopsida - conifers (3 transcripts, 3 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Chordata
Mammalia - mammals (5 transcripts, 4 species)
Amniota - vertebrates (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 1 species)
Turbellaria - flatworms (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (3 transcripts, 1 species)

Oomycetes
Peronosporales - oomycetes (1 transcript, 1 species)

 

 

 

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