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HomoloGene:68515. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MYL12B,  H.sapiens
myosin, light chain 12B, regulatory
NP_291024.1
172 aa
MYL12B,  P.troglodytes
myosin, light chain 12B, regulatory
XP_512040.1
172 aa
MYL12B,  M.mulatta
myosin, light chain 12B, regulatory
XP_001084275.1
172 aa
MYL12A,  C.lupus
myosin regulatory light polypeptide 9-like
XP_848839.1
178 aa
MYL12A,  B.taurus
myosin, light chain 12A, regulatory, non-sarcomeric
NP_001015640.1
172 aa
Myl12a,  M.musculus
myosin, light chain 12A, regulatory, non-sarcomeric
NP_080340.2
172 aa
Myl12a,  R.norvegicus
myosin, light chain 12A, regulatory, non-sarcomeric
NP_001128489.1
172 aa
MYL12A,  G.gallus
myosin, light chain 12A, regulatory, non-sarcomeric
NP_990672.1
172 aa
LOC770011,  G.gallus
myosin regulatory light chain 2, smooth muscle minor isoform-like
XP_004939810.1
172 aa
myl12b,  X.tropicalis
myosin, light chain 12B, regulatory
NP_001004813.1
172 aa
myl12.2,  D.rerio
myosin, light chain 12, genome duplicate 2
NP_001124061.1
172 aa
sqh,  D.melanogaster
spaghetti squash
NP_511057.1
174 aa
AgaP_AGAP000927,  A.gambiae
AgaP_AGAP000927
XP_003437136.1
174 aa
mlc-4,  C.elegans
mlc-4
NP_497700.1
172 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

D.melanogaster
The structural gene for cytoplasmic myosin light chain (Chang, Edwards and Kiehart, Karess, Kulkarni and Aguilera, 1991).



Publications
Articles associated with genes and sequences of this homology group.

Human nonsarcomeric 20,000 Da myosin regulatory light chain cDNA.
Grant JW, et al. Nucleic Acids Res 18, 5892 (1990).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
EFh (cd00051)
  EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
EFh (cl17302)
  EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Myl12a includes H.sapiens MYL12A.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (23 transcripts, 11 species)
Mammalia - mammals (22 transcripts, 16 species)
Cephalochordata - lancelets (17 transcripts, 1 species)
Aves - birds (7 transcripts, 3 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Amphibia - amphibians (4 transcripts, 2 species)
Amniota - vertebrates (2 transcripts, 1 species)
Hyperoartia - vertebrates (2 transcripts, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 13 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (8 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (6 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (2 transcripts, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)
Liliopsida - monocots (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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