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HomoloGene:3539. Gene conserved in Boreoeutheria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ARHGAP29,  H.sapiens
Rho GTPase activating protein 29
NP_004806.3
1261 aa
ARHGAP29,  P.troglodytes
Rho GTPase activating protein 29
XP_001156219.1
1261 aa
ARHGAP29,  M.mulatta
Rho GTPase activating protein 29
XP_001102744.1
1266 aa
ARHGAP29,  C.lupus
Rho GTPase activating protein 29
XP_537065.1
1269 aa
ARHGAP29,  B.taurus
Rho GTPase activating protein 29
NP_001095955.1
1269 aa
Arhgap29,  M.musculus
Rho GTPase activating protein 29
NP_766113.1
1266 aa
Arhgap29,  R.norvegicus
Rho GTPase activating protein 29
NP_001009405.1
1182 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Rasip1 mediates Rap1 regulation of Rho in endothelial barrier function through ArhGAP29.
Post A, et al. Proc Natl Acad Sci U S A 110, 11427-32 (2013).
PARG1, a protein-tyrosine phosphatase-associated RhoGAP, as a putative Rap2 effector.
Myagmar BE, et al. Biochem Biophys Res Commun 329, 1046-52 (2005).
Genetic predictors of fibrin D-dimer levels in healthy adults.
Smith NL, et al. Circulation 123, 1864-72 (2011).
Mutation of ARHGAP9 in patients with coronary spastic angina.
Takefuji M, et al. J Hum Genet 55, 42-9 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
RhoGAP (cl02570)
  RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
IER (pfam05760)
  Immediate early response protein (IER).
C1 (cl00040)
  Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
RhoGAP (cl02570)
  RhoGAP: GTPase-activator protein (GAP) for Rho-like GTPases; GAPs towards Rho/Rac/Cdc42-like small GTPases. Small GTPases (G proteins) cluster into distinct families, and all act as molecular switches, active in their GTP-bound form but inactive when ...
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Arhgap29 includes H.sapiens ARHGAP29 and R.norvegicus Arhgap29.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (4 transcripts, 4 species)
Amniota - vertebrates (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

 

 

 

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