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HomoloGene:10592. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

WRNIP1,  H.sapiens
Werner helicase interacting protein 1
NP_064520.2
665 aa
WRNIP1,  P.troglodytes
Werner helicase interacting protein 1
XP_003950752.1
665 aa
WRNIP1,  M.mulatta
Werner helicase interacting protein 1
XP_001090684.1
665 aa
WRNIP1,  C.lupus
Werner helicase interacting protein 1
XP_005640033.1
445 aa
WRNIP1,  B.taurus
Werner helicase interacting protein 1
NP_001096576.1
638 aa
Wrnip1,  M.musculus
Werner helicase interacting protein 1
NP_084491.3
660 aa
Wrnip1,  R.norvegicus
Werner helicase interacting protein 1
NP_758835.1
660 aa
WRNIP1,  G.gallus
Werner helicase interacting protein 1
XP_418979.2
562 aa
wrnip1,  X.tropicalis
Werner helicase interacting protein 1
NP_001121492.1
577 aa
wrnip1,  D.rerio
Werner helicase interacting protein 1
NP_998085.1
546 aa
MGS1,  S.cerevisiae
MGS1
NP_014181.1
587 aa
KLLA0D19360g,  K.lactis
KLLA0D19360g
XP_453921.1
559 aa
AGOS_ABL183W,  E.gossypii
AGOS_ABL183W
NP_982764.1
547 aa
SPAC26H5.02c,  S.pombe
SPAC26H5.02c
NP_594449.2
504 aa
MGG_17505,  M.oryzae
MGG_17505
XP_003718908.1
575 aa
NCU08706,  N.crassa
NCU08706
XP_963567.1
622 aa
AT1G24290,  A.thaliana
AT1G24290
NP_173839.1
525 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Physical and functional interaction between WRNIP1 and RAD18.
Yoshimura A, et al. Genes Genet Syst 84, 171-8 (2009).
Conjugation of complex polyubiquitin chains to WRNIP1.
Bish RA, et al. J Proteome Res 7, 3481-9 (2008).
Functional relationships between Rad18 and WRNIP1 in vertebrate cells.
Yoshimura A, et al. Biol Pharm Bull 29, 2192-6 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ZnF_Rad18 (smart00734)
  Rad18-like CCHC zinc finger.
MgsA_C (pfam12002)
  MgsA AAA+ ATPase C terminal.
UBA (cl00153)
  Ubiquitin Associated domain. The UBA domain is a commonly occurring sequence motif in some members of the ubiquitination pathway, UV excision repair proteins, and certain protein kinases. Although its specific role is so far unknown, it has been suggested that UBA domains are involved in conferring protein target specificity. The domain, a compact three helix bundle, has a conserved GFP-loop and the proline is thought to be critical for binding. The UBA domain is distinct from the conserved three helical domain seen in the N-terminus of EF-TS and eukaryotic NAC proteins.
AAA (cl18944)
  The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...
MgsA_C (cl19688)
  MgsA AAA+ ATPase C terminal.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Wrnip1 includes H.sapiens WRNIP1 and R.norvegicus Wrnip1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 10 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (6 transcripts, 4 species)
Arachnida - arachnids (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (11 transcripts, 10 species)
Bryopsida - mosses (2 transcripts, 1 species)
Coniferopsida - conifers (2 transcripts, 2 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Apicomplexa
Coccidia - apicomplexans (1 transcript, 1 species)

 

 

 

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