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HomoloGene:68478. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

NELFA,  H.sapiens
negative elongation factor complex member A
NP_005654.3
539 aa
WHSC2,  P.troglodytes
Wolf-Hirschhorn syndrome candidate 2
NP_001231577.1
539 aa
WHSC2,  M.mulatta
Wolf-Hirschhorn syndrome candidate 2
XP_001100646.2
539 aa
NELFA,  C.lupus
negative elongation factor complex member A
XP_545924.2
532 aa
WHSC2,  B.taurus
Wolf-Hirschhorn syndrome candidate 2
NP_001095823.1
533 aa
Nelfa,  M.musculus
negative elongation factor complex member A, Whsc2
NP_036044.1
530 aa
Nelfa,  R.norvegicus
negative elongation factor complex member A
NP_001008340.1
530 aa
WHSC2,  G.gallus
Wolf-Hirschhorn syndrome candidate 2
NP_001026338.1
539 aa
nelfa,  X.tropicalis
negative elongation factor complex member A
XP_002936807.1
527 aa
nelfa,  D.rerio
negative elongation factor complex member A
NP_001166972.1
542 aa
AgaP_AGAP002290,  A.gambiae
AgaP_AGAP002290
XP_001687824.2
1261 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

MicroRNA-133 controls cardiac hypertrophy.
Carè A, et al. Nat Med 13, 613-8 (2007).
[Genetic determination of Wolf-Hirschhorn syndrome ].
Gutmajster E & Rokicka A. Wiad Lek 55, 706-10 (2002).
Modulation of WHSC2 expression in human endothelial cells.
Mariotti M, et al. FEBS Lett 487, 166-70 (2000).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PRK12323 (PRK12323)
  DNA polymerase III subunits gamma and tau; Provisional.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Nelfa includes H.sapiens NELFA.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 10 species)
Actinopterygii - bony fishes (11 transcripts, 8 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (7 transcripts, 7 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)
Hydrozoa - hydrozoans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

 

 

 

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