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HomoloGene:40112. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TOMM70A,  H.sapiens
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
NP_055635.3
608 aa
TOMM70A,  P.troglodytes
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
XP_526255.2
608 aa
TOMM70A,  M.mulatta
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
XP_001092332.1
608 aa
TOMM70A,  C.lupus
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
XP_535719.3
609 aa
TOMM70A,  B.taurus
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
NP_001068796.1
609 aa
Tomm70a,  M.musculus
translocase of outer mitochondrial membrane 70 homolog A (yeast)
NP_613065.2
611 aa
Tomm70a,  R.norvegicus
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
NP_997684.1
610 aa
TOMM70A,  G.gallus
translocase of outer mitochondrial membrane 70 homolog A (S. cerevisiae)
XP_416605.2
653 aa
tomm70a,  X.tropicalis
translocase of outer mitochondrial membrane 70 homolog A
NP_001096527.1
577 aa
tomm70a,  D.rerio
translocase of outer mitochondrial membrane 70 homolog A (yeast)
NP_956296.1
578 aa
Tom70,  D.melanogaster
Translocase of outer membrane 70
NP_609536.1
589 aa
AgaP_AGAP009497,  A.gambiae
AgaP_AGAP009497
XP_310198.4
571 aa
TOM70,  S.cerevisiae
TOM70
NP_014278.3
617 aa
KLLA0F24046g,  K.lactis
KLLA0F24046g
XP_456151.1
604 aa
AGOS_ABR131W,  E.gossypii
AGOS_ABR131W
NP_983078.1
594 aa
tom70,  S.pombe
tom70
NP_593767.1
625 aa
MGG_00979,  M.oryzae
MGG_00979
XP_003717970.1
622 aa
NCU04245,  N.crassa
NCU04245
XP_961236.1
624 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Human mitochondrial import receptor Tom70 functions as a monomer.
Fan AC, et al. Biochem J 429, 553-63 (2010).
Preliminary X-ray crystallographic studies of yeast mitochondrial protein Tom70p.
Wu Y, et al. Acta Crystallogr Sect F Struct Biol Cryst Commun 62, 265-7 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
TPR_16 (pfam13432)
  Tetratricopeptide repeat.
TPR_11 (pfam13414)
  TPR repeat.
TPR (cd00189)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR (cl02429)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR_16 (pfam13432)
  Tetratricopeptide repeat.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tomm70a includes H.sapiens TOMM70A and R.norvegicus Tomm70a.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 14 species)
Actinopterygii - bony fishes (14 transcripts, 10 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Aves - birds (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (14 transcripts, 12 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (1 transcript, 1 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (6 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (2 transcripts, 1 species)

Streptophyta
Liliopsida - monocots (1 transcript, 1 species)
Coniferopsida - conifers (1 transcript, 1 species)

 

 

 

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