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HomoloGene:2893. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ST3GAL5,  H.sapiens
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
NP_003887.3
418 aa
ST3GAL5,  P.troglodytes
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
NP_001032378.1
362 aa
ST3GAL5,  M.mulatta
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
XP_001090769.2
418 aa
ST3GAL5,  C.lupus
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
XP_854842.2
421 aa
ST3GAL5,  B.taurus
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
NP_991376.2
420 aa
St3gal5,  M.musculus
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
NP_001030305.1
414 aa
St3gal5,  R.norvegicus
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
NP_112627.2
387 aa
ST3GAL5,  G.gallus
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
NP_001001192.1
368 aa
st3gal5,  X.tropicalis
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
NP_001165301.1
372 aa
st3gal5,  D.rerio
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
NP_955810.2
364 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Amish infantile epilepsy syndrome.



Publications
Articles associated with genes and sequences of this homology group.

CD4 and CD8 T cells require different membrane gangliosides for activation.
Nagafuku M, et al. Proc Natl Acad Sci U S A 109, E336-42 (2012).
Impairment of neuropsychological behaviors in ganglioside GM3-knockout mice.
Niimi K, et al. Biochem Biophys Res Commun 406, 524-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Glyco_transf_29 (pfam00777)
  Glycosyltransferase family 29 (sialyltransferase).
Glyco_transf_29 (pfam00777)
  Glycosyltransferase family 29 (sialyltransferase).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus St3gal5 includes H.sapiens ST3GAL5 and R.norvegicus St3gal5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (17 transcripts, 16 species)
Actinopterygii - bony fishes (5 transcripts, 4 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

 

 

 

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