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HomoloGene:32171. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SNX10,  H.sapiens
sorting nexin 10
NP_001186764.1
201 aa
SNX10,  P.troglodytes
sorting nexin 10
XP_001161647.2
227 aa
SNX10,  M.mulatta
sorting nexin 10
XP_001094160.1
201 aa
SNX10,  C.lupus
sorting nexin 10
XP_005628707.1
201 aa
SNX10,  B.taurus
sorting nexin 10
NP_001068843.1
200 aa
Snx10,  M.musculus
sorting nexin 10
NP_082311.3
201 aa
Snx10,  R.norvegicus
sorting nexin 10
NP_001013103.1
201 aa
SNX10,  G.gallus
sorting nexin 10
NP_001026157.1
201 aa
snx10,  X.tropicalis
sorting nexin 10
NP_001011114.1
171 aa
snx10a,  D.rerio
sorting nexin 10a
NP_001132934.1
229 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

An SNX10 mutation causes malignant osteopetrosis of infancy.
Aker M, et al. J Med Genet 49, 221-6 (2012).
Sorting nexin 10 induces giant vacuoles in mammalian cells.
Qin B, et al. J Biol Chem 281, 36891-6 (2006).
SNX10 is required for osteoclast formation and resorption activity.
Zhu CH, et al. J Cell Biochem 113, 1608-15 (2012).
Sorting out the cellular functions of sorting nexins.
Worby CA & Dixon JE. Nat Rev Mol Cell Biol 3, 919-31 (2002).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PX_domain (cl02563)
  The Phox Homology domain, a phosphoinositide binding module.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Snx10 includes H.sapiens SNX10 and R.norvegicus Snx10.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 11 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

 

 

 

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