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HomoloGene:11155. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SLC39A8,  H.sapiens
solute carrier family 39 (zinc transporter), member 8
NP_001128618.1
460 aa
SLC39A8,  P.troglodytes
solute carrier family 39 (zinc transporter), member 8
XP_001168404.1
460 aa
LOC710142,  M.mulatta
solute carrier family 39 (zinc transporter), member 8
XP_002808462.1
460 aa
SLC39A8,  C.lupus
solute carrier family 39 (zinc transporter), member 8
XP_005639290.1
461 aa
SLC39A8,  B.taurus
solute carrier family 39 (zinc transporter), member 8
NP_001192559.1
461 aa
Slc39a8,  M.musculus
solute carrier family 39 (metal ion transporter), member 8
NP_001128621.1
462 aa
Slc39a8,  R.norvegicus
solute carrier family 39 (zinc transporter), member 8
NP_001011952.1
462 aa
SLC39A8,  G.gallus
solute carrier family 39 (zinc transporter), member 8
XP_427970.3
450 aa
slc39a8,  X.tropicalis
solute carrier family 39 (zinc transporter), member 8
XP_002934812.1
459 aa
LOC100002893,  D.rerio
zinc transporter ZIP8-like
XP_001342563.3
443 aa
LOC101885679,  D.rerio
zinc transporter ZIP8-like
XP_005156653.1
270 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The human zinc transporter SLC39A8 (Zip8) is critical in zinc-mediated cytoprotection in lung epithelia.
Besecker B, et al. Am J Physiol Lung Cell Mol Physiol 294, L1127-36 (2008).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Zip (pfam02535)
  ZIP Zinc transporter.
Zip (cl00437)
  ZIP Zinc transporter.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc39a8 includes H.sapiens SLC39A8 and R.norvegicus Slc39a8.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (12 transcripts, 11 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Ascidiacea - tunicates (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (3 transcripts, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

 

 

 

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