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HomoloGene:130007. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SLC16A12,  H.sapiens
solute carrier family 16, member 12
NP_998771.3
516 aa
SLC16A12,  P.troglodytes
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
XP_507905.3
516 aa
SLC16A12,  M.mulatta
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
XP_001086787.1
486 aa
SLC16A12,  C.lupus
solute carrier family 16, member 12
XP_005637574.1
490 aa
SLC16A12,  B.taurus
solute carrier family 16, member 12
XP_002698390.2
517 aa
Slc16a12,  M.musculus
solute carrier family 16 (monocarboxylic acid transporters), member 12
NP_766426.1
486 aa
Slc16a12,  R.norvegicus
solute carrier family 16, member 12
NP_001178566.1
486 aa
SLC16A12,  G.gallus
solute carrier family 16, member 12 (monocarboxylic acid transporter 12)
XP_004942200.1
641 aa
slc16a12,  X.tropicalis
solute carrier family 16, member 12
NP_989310.1
473 aa
slc16a12b,  D.rerio
solute carrier family 16 (monocarboxylic acid transporters), member 12b
NP_001139286.1
488 aa
Mct1,  D.melanogaster
Monocarboxylate transporter 1
NP_477334.2
626 aa
AgaP_AGAP000040,  A.gambiae
AgaP_AGAP000040
XP_311120.3
606 aa
C10E2.6,  C.elegans
C10E2.6
NP_510705.1
594 aa
T02G5.12,  C.elegans
T02G5.12
NP_495464.2
591 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Cataract, juvenile, with microcornea and glucosuria.



Publications
Articles associated with genes and sequences of this homology group.

Alterations of the 5'untranslated region of SLC16A12 lead to age-related cataract.
Zuercher J, et al. Invest Ophthalmol Vis Sci 51, 3354-61 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
MFS (cd06174)
  The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
2A0113 (TIGR00892)
  monocarboxylate transporter 1.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc16a12 includes H.sapiens SLC16A12 and R.norvegicus Slc16a12.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (8 transcripts, 7 species)
Actinopterygii - bony fishes (6 transcripts, 6 species)
Aves - birds (2 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (2 transcripts, 2 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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