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HomoloGene:21373. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

RXRG,  H.sapiens
retinoid X receptor, gamma
NP_008848.1
463 aa
RXRG,  P.troglodytes
retinoid X receptor, gamma
XP_513962.2
463 aa
RXRG,  M.mulatta
retinoid X receptor, gamma
XP_001085084.1
463 aa
RXRG,  C.lupus
retinoid X receptor, gamma
XP_536146.2
463 aa
RXRG,  B.taurus
retinoid X receptor, gamma
NP_001068876.1
463 aa
Rxrg,  M.musculus
retinoid X receptor gamma
NP_033133.1
463 aa
Rxrg,  R.norvegicus
retinoid X receptor gamma
NP_113953.1
463 aa
RXRG,  G.gallus
retinoid X receptor, gamma
NP_990625.1
467 aa
rxrg,  X.tropicalis
retinoid X receptor, gamma
XP_002933799.1
468 aa
rxrgb,  D.rerio
retinoid X receptor, gamma b
NP_001002345.1
452 aa
rxrga,  D.rerio
retinoid x receptor, gamma a
NP_571292.2
441 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

RXRγ gene variants are associated with HIV lipodystrophy.
Pushpakom SP, et al. Pharmacogenet Genomics 23, 438-41 (2013).
Adaptive evolution of the Retinoid X receptor in vertebrates.
Philip S, et al. Genomics 99, 81-9 (2012).
The retinoid X receptors and their ligands.
Dawson MI & Xia Z. Biochim Biophys Acta 1821, 21-56 (2012).
An RXR-γ Rx for white-matter damage.
Gallo V & Chew LJ. Nat Neurosci 14, 3-5 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Nuc_recep-AF1 (pfam11825)
  Nuclear/hormone receptor activator site AF-1.
Nuc_recep-AF1 (pfam11825)
  Nuclear/hormone receptor activator site AF-1.
NR_DBD_like (cl02596)
  DNA-binding domain of nuclear receptors is composed of two C4-type zinc fingers.
NR_LBD (cl11397)
  The ligand binding domain of nuclear receptors, a family of ligand-activated transcription regulators.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Rxrg includes H.sapiens RXRG and R.norvegicus Rxrg.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (23 transcripts, 10 species)
Mammalia - mammals (15 transcripts, 13 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Aves - birds (4 transcripts, 2 species)
Amphibia - amphibians (4 transcripts, 2 species)

Arthropoda
Insecta - insects (6 transcripts, 6 species)
Arachnida - arachnids (4 transcripts, 2 species)
Branchiopoda - crustaceans (2 transcripts, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

 

 

 

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