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HomoloGene:56741. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DESI2,  H.sapiens
desumoylating isopeptidase 2
NP_057160.2
194 aa
DESI2,  P.troglodytes
desumoylating isopeptidase 2
XP_003949780.1
211 aa
PPPDE1,  M.mulatta
PPPDE peptidase domain containing 1
XP_001102905.2
194 aa
DESI2,  C.lupus
desumoylating isopeptidase 2
XP_005622658.1
193 aa
PPPDE1,  B.taurus
PPPDE peptidase domain containing 1
NP_001093854.1
178 aa
Desi2,  M.musculus
desumoylating isopeptidase 2
NP_077244.1
194 aa
Desi2,  R.norvegicus
desumoylating isopeptidase 2
NP_001013895.1
194 aa
PPPDE1,  G.gallus
PPPDE peptidase domain containing 1
NP_001008460.1
193 aa
desi2,  X.tropicalis
desumoylating isopeptidase 2
XP_002942241.1
194 aa
desi2,  D.rerio
desumoylating isopeptidase 2
NP_001003532.1
196 aa
CG7222,  D.melanogaster
CG7222
NP_610613.1
205 aa
AgaP_AGAP012058,  A.gambiae
AgaP_AGAP012058
XP_320465.2
203 aa
F36D4.5,  C.elegans
F36D4.5
NP_741591.1
334 aa
AT4G17486,  A.thaliana
AT4G17486
NP_567528.2
224 aa
AT5G47310,  A.thaliana
AT5G47310
NP_199542.1
245 aa
Os03g0100900,  O.sativa
Os03g0100900
NP_001048648.1
245 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

PNAS-4 expression and its relationship to p53 in colorectal cancer.
Zhou B, et al. Mol Biol Rep 39, 243-9 (2012).
DeSUMOylating isopeptidase: a second class of SUMO protease.
Shin EJ, et al. EMBO Rep 13, 339-46 (2012).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DUF862 (pfam05903)
  PPPDE putative peptidase domain.
Peptidase_C97 (pfam05903)
  PPPDE putative peptidase domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Desi2 includes H.sapiens DESI2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (46 transcripts, 27 species)
Liliopsida - monocots (14 transcripts, 8 species)
Isoetopsida - club-mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Chordata
Mammalia - mammals (10 transcripts, 9 species)
Actinopterygii - bony fishes (7 transcripts, 6 species)
Amphibia - amphibians (2 transcripts, 2 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (9 transcripts, 9 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (2 transcripts, 2 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

 

 

 

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