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HomoloGene:3281. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

FDFT1,  H.sapiens
farnesyl-diphosphate farnesyltransferase 1
NP_001274671.1
417 aa
FDFT1,  P.troglodytes
farnesyl-diphosphate farnesyltransferase 1
XP_001141492.1
417 aa
FDFT1,  M.mulatta
farnesyl-diphosphate farnesyltransferase 1
XP_001086419.1
417 aa
FDFT1,  C.lupus
farnesyl-diphosphate farnesyltransferase 1
XP_534557.2
417 aa
FDFT1,  B.taurus
farnesyl-diphosphate farnesyltransferase 1
NP_001013022.1
417 aa
Fdft1,  M.musculus
farnesyl diphosphate farnesyl transferase 1
NP_034321.2
416 aa
Fdft1,  R.norvegicus
farnesyl diphosphate farnesyl transferase 1
NP_062111.1
416 aa
FDFT1,  G.gallus
farnesyl-diphosphate farnesyltransferase 1
NP_001034383.1
418 aa
fdft1,  X.tropicalis
farnesyl-diphosphate farnesyltransferase 1
NP_001135642.2
416 aa
si:ch73-107c13.2,  D.rerio
si:ch73-107c13.2
NP_001189454.1
418 aa
ERG9,  S.cerevisiae
ERG9
NP_012060.1
444 aa
KLLA0D08866g,  K.lactis
KLLA0D08866g
XP_453457.1
441 aa
AGOS_AFR444C,  E.gossypii
AGOS_AFR444C
NP_985991.1
441 aa
erg9,  S.pombe
erg9
NP_595363.1
460 aa
MGG_09239,  M.oryzae
MGG_09239
XP_003709863.1
465 aa
NCU06054,  N.crassa
NCU06054
XP_959817.1
481 aa
SQS2,  A.thaliana
SQS2
NP_195191.2
413 aa
SQS1,  A.thaliana
SQS1
NP_195190.1
410 aa
Os03g0805100,  O.sativa
Os03g0805100
NP_001051625.1
403 aa
Os07g0200700,  O.sativa
Os07g0200700
NP_001059129.1
410 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Construction of carotenoid biosynthetic pathways using squalene synthase.
Furubayashi M, et al. FEBS Lett 588, 436-42 (2014).
Survival of adult neurons lacking cholesterol synthesis in vivo.
F├╝nfschilling U, et al. BMC Neurosci 8, 1 (2007).
Comparative squalene synthase gene expression in mouse liver and testis.
Collins BS, et al. Arch Biochem Biophys 395, 253-8 (2001).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Isoprenoid_Biosyn_C1 (cl00210)
  Isoprenoid Biosynthesis enzymes, Class 1.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Fdft1 includes H.sapiens FDFT1 and R.norvegicus Fdft1.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (52 transcripts, 33 species)
Liliopsida - monocots (12 transcripts, 9 species)
Coniferopsida - conifers (3 transcripts, 3 species)
Bryopsida - mosses (1 transcript, 1 species)

Chordata
Mammalia - mammals (20 transcripts, 15 species)
Actinopterygii - bony fishes (9 transcripts, 8 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (5 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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