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HomoloGene:11345. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ADCK3,  H.sapiens
aarF domain containing kinase 3
NP_064632.2
647 aa
ADCK3,  P.troglodytes
aarF domain containing kinase 3
XP_514248.3
541 aa
ADCK3,  M.mulatta
aarF domain containing kinase 3
XP_001089596.1
647 aa
ADCK3,  C.lupus
aarF domain containing kinase 3
XP_005623029.1
630 aa
ADCK3,  B.taurus
aarF domain containing kinase 3
NP_001039884.1
648 aa
Adck3,  M.musculus
aarF domain containing kinase 3
NP_075830.2
645 aa
Adck3,  R.norvegicus
aarF domain containing kinase 3
NP_001013203.1
649 aa
ADCK3,  G.gallus
aarF domain containing kinase 3
NP_001186342.1
648 aa
adck3,  X.tropicalis
aarF domain containing kinase 3
XP_002938888.1
644 aa
adck3,  D.rerio
aarF domain containing kinase 3
NP_001002728.2
619 aa
coq-8,  C.elegans
coq-8
NP_498014.2
755 aa
COQ8,  S.cerevisiae
COQ8
NP_011396.1
501 aa
KLLA0B00539g,  K.lactis
KLLA0B00539g
XP_451554.1
557 aa
AGOS_AAR181W,  E.gossypii
AGOS_AAR181W
NP_982724.1
543 aa
abc1,  S.pombe
abc1
NP_596237.1
610 aa
MGG_06939,  M.oryzae
MGG_06939
XP_003709679.1
726 aa
NCU03823,  N.crassa
NCU03823
XP_961212.1
774 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Coenzyme Q10 deficiency.
Spinocerebellar ataxia, autosomal recessive 9.



Publications
Articles associated with genes and sequences of this homology group.

Adult-onset cerebellar ataxia due to mutations in CABC1/ADCK3.
Horvath R, et al. J Neurol Neurosurg Psychiatry 83, 174-8 (2012).
Coenzyme Q supports distinct developmental processes in Caenorhabditis elegans.
Asencio C, et al. Mech Ageing Dev 130, 145-53 (2009).
A collection of cDNAs enriched in upper cortical layers of the embryonic mouse brain.
GarcĂ­a-Frigola C, et al. Brain Res Mol Brain Res 122, 133-50 (2004).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ABC1 (cl17513)
  ABC1 family.
APH_ChoK_like (cl17270)
  Aminoglycoside 3'-phosphotransferase (APH) and Choline Kinase (ChoK) family. The APH/ChoK family is part of a larger superfamily that includes the catalytic domains of other kinases, such as the typical serine/threonine/tyrosine protein kinases (PKs) ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Adck3 includes H.sapiens ADCK3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (20 transcripts, 10 species)
Mammalia - mammals (13 transcripts, 11 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

 

 

 

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