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HomoloGene:78213. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IFIT1,  H.sapiens
interferon-induced protein with tetratricopeptide repeats 1
NP_001539.3
478 aa
IFIT1,  P.troglodytes
interferon-induced protein with tetratricopeptide repeats 1
NP_001192276.1
478 aa
IFIT1,  M.mulatta
interferon-induced protein with tetratricopeptide repeats 1
XP_001086535.1
478 aa
IFIT1,  C.lupus
interferon-induced protein with tetratricopeptide repeats 1
XP_848364.1
480 aa
IFIT1B,  C.lupus
interferon-induced protein with tetratricopeptide repeats 1B
XP_848342.2
488 aa
IFIT1,  B.taurus
interferon-induced protein with tetratricopeptide repeats 1
XP_002698403.2
454 aa
Gm14446,  M.musculus
predicted gene 14446
NP_001103987.1
470 aa
2010002M12Rik,  M.musculus
RIKEN cDNA 2010002M12 gene
NP_444447.1
466 aa
Ifit1lb,  R.norvegicus
interferon-induced protein with tetratricopeptide repeats 1-like B
XP_220058.2
473 aa
ifit5,  X.tropicalis
interferon-induced protein with tetratricopeptide repeats 5
NP_001135660.1
473 aa
si:dkey-26g8.12,  D.rerio
si:dkey-26g8.12
XP_005169517.1
469 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The ISG56/IFIT1 gene family.
Fensterl V & Sen GC. J Interferon Cytokine Res 31, 71-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
type_IV_pilW (TIGR02521)
  type IV pilus biogenesis/stability protein PilW.
TPR_1 (pfam00515)
  Tetratricopeptide repeat.
TPR_12 (pfam13424)
  Tetratricopeptide repeat.
TPR_16 (pfam13432)
  Tetratricopeptide repeat.
TPR_11 (pfam13414)
  TPR repeat.
KpsS (COG3562)
  Capsule polysaccharide export protein [Cell envelope biogenesis, outer membrane].
TPR (cd00189)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR (cl02429)
  Tetratricopeptide repeat domain; typically contains 34 amino acids [WLF]-X(2)-[LIM]-[GAS]-X(2)-[YLF]-X(8)-[ASE]-X(3)-[FYL]-X(2)-[ASL]-X(4)-[PKE] is the consensus sequence; found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, ...
TPR_11 (pfam13414)
  TPR repeat.
TPR_12 (pfam13424)
  Tetratricopeptide repeat.
TPR_1 (cl02429)
  Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


 

 

 

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