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HomoloGene:7650. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ASPM,  H.sapiens
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
NP_060606.3
3477 aa
ASPM,  P.troglodytes
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
NP_001008994.1
3477 aa
ASPM,  M.mulatta
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
NP_001098005.1
3479 aa
ASPM,  C.lupus
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
NP_001184005.1
3469 aa
ASPM,  B.taurus
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
NP_001193435.1
3461 aa
Aspm,  M.musculus
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
NP_033921.3
3122 aa
Aspm,  R.norvegicus
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
NP_001099425.2
3133 aa
ASPM,  G.gallus
asp (abnormal spindle) homolog, microcephaly associated (Drosophila)
XP_422197.4
3396 aa
aspm,  X.tropicalis
asp (abnormal spindle) homolog, microcephaly associated
XP_002932224.2
3498 aa
aspm,  D.rerio
asp (abnormal spindle)-like, microcephaly associated (Drosophila)
NP_001116845.1
3391 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Microcephaly, primary autosomal recessive, 5.



Publications
Articles associated with genes and sequences of this homology group.

ASPM gene expression in medulloblastoma.
Vulcani-Freitas TM, et al. Childs Nerv Syst 27, 71-4 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CAMSAP_CH (pfam11971)
  CAMSAP CH domain.
CH (cl00030)
  Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
CH (cl00030)
  Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Aspm includes H.sapiens ASPM and R.norvegicus Aspm.


 

 

 

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