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HomoloGene:68419. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

SLC4A8,  H.sapiens
solute carrier family 4, sodium bicarbonate cotransporter, member 8
NP_001035049.1
1093 aa
SLC4A8,  M.mulatta
solute carrier family 4, sodium bicarbonate cotransporter, member 8
XP_001090180.1
1093 aa
SLC4A8,  C.lupus
solute carrier family 4, sodium bicarbonate cotransporter, member 8
XP_005636865.1
1055 aa
SLC4A8,  B.taurus
solute carrier family 4, sodium bicarbonate cotransporter, member 8
XP_002687339.3
1092 aa
Slc4a8,  M.musculus
solute carrier family 4 (anion exchanger), member 8
NP_067505.2
1089 aa
Slc4a8,  R.norvegicus
solute carrier family 4, sodium bicarbonate cotransporter, member 8
NP_001257723.1
1037 aa
LOC425441,  G.gallus
electroneutral sodium bicarbonate exchanger 1-like
XP_004949806.1
1023 aa
slc4a8,  X.tropicalis
solute carrier family 4, sodium bicarbonate cotransporter, member 8
XP_002933752.2
1096 aa
slc4a8,  D.rerio
solute carrier family 4, sodium bicarbonate cotransporter, member 8
XP_685666.5
1105 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The sodium-driven chloride/bicarbonate exchanger in presynaptic terminals.
Burette AC, et al. J Comp Neurol 520, 1481-92 (2012).
Na+:HCO3- cotransporters (NBC): expression and regulation in the kidney.
Soleimani M. J Nephrol 15 Suppl 5, S32-40 (2002).
Characterization of Na+/HCO-3 cotransporter isoform NBC-3.
Amlal H, et al. Am J Physiol 276, F903-13 (1999).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
ae (TIGR00834)
  anion exchange protein.
HCO3_cotransp (pfam00955)
  HCO3- transporter family.
PTS_IIA_fru (cl00163)
  PTS_IIA, PTS system, fructose/mannitol specific IIA subunit. The bacterial phosphoenolpyruvate: sugar phosphotransferase system (PTS) is a multi-protein system involved in the regulation of a variety of metabolic and transcriptional processes. This ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Slc4a8 includes H.sapiens SLC4A8 and R.norvegicus Slc4a8.


 

 

 

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