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HomoloGene:5605. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

VPS54,  H.sapiens
vacuolar protein sorting 54 homolog (S. cerevisiae)
NP_057600.2
977 aa
VPS54,  P.troglodytes
vacuolar protein sorting 54 homolog (S. cerevisiae)
XP_515511.2
965 aa
VPS54,  M.mulatta
vacuolar protein sorting 54 homolog (S. cerevisiae)
XP_001087667.1
977 aa
VPS54,  C.lupus
vacuolar protein sorting 54 homolog (S. cerevisiae)
XP_865972.2
977 aa
VPS54,  B.taurus
vacuolar protein sorting 54 homolog (S. cerevisiae)
NP_001098930.1
977 aa
Vps54,  M.musculus
vacuolar protein sorting 54 (yeast)
NP_620692.3
977 aa
Vps54,  R.norvegicus
vacuolar protein sorting 54 homolog (S. cerevisiae)
NP_775170.1
965 aa
VPS54,  G.gallus
vacuolar protein sorting 54 homolog (S. cerevisiae)
XP_419349.3
974 aa
vps54,  X.tropicalis
vacuolar protein sorting 54 homolog
XP_004914765.1
981 aa
vps54,  D.rerio
vacuolar protein sorting 54 homolog (S. cerevisiae)
NP_001124248.1
998 aa
scat,  D.melanogaster
scattered
NP_524905.1
940 aa
AgaP_AGAP008353,  A.gambiae
AgaP_AGAP008353
XP_317102.3
883 aa
vps-54,  C.elegans
vps-54
NP_001256226.1
1058 aa
VPS54,  A.thaliana
VPS54
NP_849409.2
1034 aa
Os04g0212100,  O.sativa
Os04g0212100
NP_001173796.1
411 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Progesterone prevents mitochondrial dysfunction in the spinal cord of wobbler mice.
Gonzalez Deniselle MC, et al. J Neurochem 122, 185-95 (2012).
VPS54 genetic analysis in ALS Italian cohort.
Corrado L, et al. Eur J Neurol 18, e41-2 (2011).
Evaluation of the Golgi trafficking protein VPS54 (wobbler) as a candidate for ALS.
Meisler MH, et al. Amyotroph Lateral Scler 9, 141-8 (2008).
Transcription factor p53 in degenerating spinal cords.
Eve DJ, et al. Brain Res 1150, 174-81 (2007).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Vps54 (pfam07928)
  Vps54-like protein.
DUF2450 (pfam10475)
  Protein of unknown function N-terminal domain (DUF2450).
DUF2450 (cl19949)
  Protein of unknown function N-terminal domain (DUF2450).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Vps54 includes H.sapiens VPS54 and R.norvegicus Vps54.


 

 

 

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