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HomoloGene:32695. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

LRPPRC,  H.sapiens
leucine-rich pentatricopeptide repeat containing
NP_573566.2
1394 aa
LRPPRC,  P.troglodytes
leucine-rich pentatricopeptide repeat containing
XP_001143797.1
1394 aa
LRPPRC,  M.mulatta
leucine-rich pentatricopeptide repeat containing
XP_001107298.2
1373 aa
LRPPRC,  C.lupus
leucine-rich pentatricopeptide repeat containing
XP_531800.2
1393 aa
LRPPRC,  B.taurus
leucine-rich pentatricopeptide repeat containing
XP_002691297.2
1394 aa
Lrpprc,  M.musculus
leucine-rich PPR-motif containing
NP_082509.2
1392 aa
Lrpprc,  R.norvegicus
leucine-rich pentatricopeptide repeat containing
NP_001008519.1
1392 aa
LRPPRC,  G.gallus
leucine-rich pentatricopeptide repeat containing
XP_001234903.3
1371 aa
lrpprc,  X.tropicalis
leucine-rich pentatricopeptide repeat containing
NP_001039203.1
1391 aa
lrpprc,  D.rerio
leucine-rich PPR-motif containing
NP_001136064.1
1436 aa
bsf,  D.melanogaster
bicoid stability factor
NP_523596.2
1412 aa
AgaP_AGAP008770,  A.gambiae
AgaP_AGAP008770
XP_557938.3
1397 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Leigh syndrome, French-Canadian type.



Publications
Articles associated with genes and sequences of this homology group.

LRPPRC is a mitochondrial matrix protein that is conserved in metazoans.
Sterky FH, et al. Biochem Biophys Res Commun 398, 759-64 (2010).
Mitochondrial and nuclear genomic responses to loss of LRPPRC expression.
Gohil VM, et al. J Biol Chem 285, 13742-7 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PPR (pfam01535)
  PPR repeat.
PPR_1 (pfam12854)
  PPR repeat.
PPR_2 (pfam13041)
  PPR repeat family.
Pterin_binding (cl00219)
  Pterin binding enzymes. This family includes dihydropteroate synthase (DHPS) and cobalamin-dependent methyltransferases such as methyltetrahydrofolate, corrinoid iron-sulfur protein methyltransferase (MeTr) and methionine synthase (MetH). DHPS, a ...
PPR_2 (cl03252)
  PPR repeat family.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lrpprc includes H.sapiens LRPPRC and R.norvegicus Lrpprc.


 

 

 

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