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HomoloGene:32357. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ASPN,  H.sapiens
asporin
NP_060150.4
379 aa
ASPN,  P.troglodytes
asporin
XP_001146178.1
378 aa
ASPN,  C.lupus
asporin
XP_005616051.1
372 aa
ASPN,  B.taurus
asporin
NP_001029481.1
370 aa
Aspn,  M.musculus
asporin
NP_079987.2
373 aa
Aspn,  R.norvegicus
asporin
NP_001014030.1
375 aa
ASPN,  G.gallus
asporin
XP_414298.2
371 aa
aspn,  X.tropicalis
asporin
XP_002934272.1
378 aa
aspn,  D.rerio
asporin (LRR class 1)
NP_571788.2
370 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Osteoarthritis, susceptibility to.



Publications
Articles associated with genes and sequences of this homology group.

Association study of candidate genes for the progression of hand osteoarthritis.
Bijsterbosch J, et al. Osteoarthritis Cartilage 21, 565-9 (2013).
The role of asporin in mineralization of human dental pulp stem cells.
Lee EH, et al. J Cell Physiol 226, 1676-82 (2011).
Binding characteristics of the osteoarthritis-associated protein asporin.
Kou I, et al. J Bone Miner Metab 28, 395-402 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
LRR_8 (pfam13855)
  Leucine rich repeat.
LRRNT (cl02423)
  Leucine rich repeat N-terminal domain.
LRR_8 (pfam13855)
  Leucine rich repeat.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Aspn includes H.sapiens ASPN and R.norvegicus Aspn.


 

 

 

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