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HomoloGene:31251. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

BRPF1,  H.sapiens
bromodomain and PHD finger containing, 1
NP_001003694.1
1220 aa
BRPF1,  P.troglodytes
bromodomain and PHD finger containing, 1
XP_003309650.1
1220 aa
BRPF1,  M.mulatta
bromodomain and PHD finger containing, 1
XP_001094039.1
1220 aa
BRPF1,  C.lupus
bromodomain and PHD finger containing, 1
XP_850615.1
1220 aa
BRPF1,  B.taurus
bromodomain and PHD finger containing, 1
NP_001193018.1
1219 aa
Brpf1,  M.musculus
bromodomain and PHD finger containing, 1
NP_001269055.1
1247 aa
Brpf1,  R.norvegicus
bromodomain and PHD finger containing, 1
NP_001178501.1
1246 aa
BRPF1,  G.gallus
bromodomain and PHD finger containing, 1
NP_001026635.1
1218 aa
brpf1,  X.tropicalis
bromodomain and PHD finger containing, 1
NP_001106468.1
930 aa
brpf1,  D.rerio
bromodomain and PHD finger containing, 1
NP_957310.1
899 aa
Br140,  D.melanogaster
Br140
NP_610266.1
1430 aa
AgaP_AGAP007617,  A.gambiae
AgaP_AGAP007617
XP_564621.3
1174 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Gene BR140, which is related to AF10 and AF17, maps to chromosome band 3p25.
Gregorini A, et al. Genes Chromosomes Cancer 17, 269-72 (1996).
BR140, a novel zinc-finger protein with homology to the TAF250 subunit of TFIID.
Thompson KA, et al. Biochem Biophys Res Commun 198, 1143-52 (1994).
Molecular basis of histone H3K36me3 recognition by the PWWP domain of Brpf1.
Vezzoli A, et al. Nat Struct Mol Biol 17, 617-9 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
zf-HC5HC2H_2 (pfam13832)
  PHD-zinc-finger like domain.
RING (cl15348)
  RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
EPL1 (pfam10513)
  Enhancer of polycomb-like.
PHD_2 (pfam13831)
  PHD-finger.
Bromodomain (cl02556)
  Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
EPL1 (pfam10513)
  Enhancer of polycomb-like.
Bromodomain (cl02556)
  Bromodomain. Bromodomains are found in many chromatin-associated proteins and in nuclear histone acetyltransferases. They interact specifically with acetylated lysine.
PWWP (cl02554)
  The PWWP domain, named for a conserved Pro-Trp-Trp-Pro motif, is a small domain consisting of 100-150 amino acids. The PWWP domain is found in numerous proteins that are involved in cell division, growth and differentiation. Most PWWP-domain proteins ...
CactinC_cactus (cl10717)
  Cactus-binding C-terminus of cactin protein.
PHD (cl17445)
  PHD-finger.
zf-HC5HC2H (cl17725)
  PHD-like zinc-binding domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Brpf1 includes H.sapiens BRPF1 and R.norvegicus Brpf1.


 

 

 

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