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HomoloGene

Discover Homologs

HomoloGene:25536. Gene conserved in Bilateria

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Genes Genes identified as putative homologs of one another during the construction of HomoloGene.			Proteins Proteins used in sequence comparisons and their conserved domain architectures.
	HEATR5B, H.sapiens HEAT repeat containing 5B			NP_061897.1 2071 aa
	HEATR5B, P.troglodytes HEAT repeat containing 5B			XP_515406.2 2071 aa
	HEATR5B, M.mulatta HEAT repeat containing 5B			XP_002799261.1 2001 aa
	HEATR5B, C.lupus HEAT repeat containing 5B			XP_540148.2 2070 aa
	LOC540503, B.taurus HEAT repeat-containing protein 5B-like			XP_005212763.1 2070 aa
	Heatr5b, M.musculus HEAT repeat containing 5B			NP_001074648.1 2070 aa
	Heatr5b, R.norvegicus HEAT repeat containing 5B			NP_001177993.1 2031 aa
	HEATR5B, G.gallus HEAT repeat containing 5B			XP_419518.2 2073 aa
	heatr5b, X.tropicalis HEAT repeat containing 5B			NP_001090701.1 2052 aa
	heatr5b, D.rerio HEAT repeat containing 5B			XP_001920896.3 1619 aa
	CG2747, D.melanogaster CG2747			NP_001262363.1 2161 aa
	AgaP_AGAP002215, A.gambiae AgaP_AGAP002215			XP_307970.5 2176 aa
	C13F10.4, C.elegans C13F10.4			NP_504828.1 2076 aa

Protein Alignments

Protein multiple alignment, pairwise similarity scores and evolutionary distances.

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Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST

Regenerate Alignments

Publications Articles associated with genes and sequences of this homology group.
Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics. Lamberti A, et al. Biochimie 93, 1738-46 (2011).
Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction. Sotoodehnia N, et al. Nat Genet 42, 1068-76 (2010).
Gene variants associated with ischemic stroke: the cardiovascular health study. Luke MM, et al. Stroke 40, 363-8 (2009).
Association of gene variants with incident myocardial infarction in the Cardiovascular Health Study. Shiffman D, et al. Arterioscler Thromb Vasc Biol 28, 173-9 (2008).

Conserved Domains Conserved Domains from CDD found in protein sequences by rpsblast searching.
HEAT_2 (pfam13646) HEAT repeats.

Related Homology Resources Links to curated and computed homology information found in other databases.
MGI:2444098 Orthology group for M.musculus Heatr5b includes H.sapiens HEATR5B and R.norvegicus Heatr5b.

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