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HomoloGene:22878. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

LPHN3,  H.sapiens
latrophilin 3
NP_056051.2
1469 aa
LPHN3,  P.troglodytes
latrophilin 3
XP_001134818.2
1469 aa
LPHN3,  M.mulatta
latrophilin 3
XP_001101643.2
1469 aa
LOC482166,  C.lupus
latrophilin-3-like
XP_005628292.1
1580 aa
LPHN3,  B.taurus
latrophilin 3
NP_851376.1
1580 aa
Lphn3,  M.musculus
latrophilin 3
NP_941991.1
1543 aa
Lphn3,  R.norvegicus
latrophilin 3
NP_570835.1
1550 aa
LPHN3,  G.gallus
latrophilin 3
XP_004941199.1
1503 aa
LOC100498069,  X.tropicalis
latrophilin-3-like
XP_004911494.1
1304 aa
lphn3.1,  D.rerio
latrophilin 3.1
XP_005170997.1
1540 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Toward a better understanding of ADHD: LPHN3 gene variants and the susceptibility to develop ADHD.
Arcos-Burgos M & Muenke M. Atten Defic Hyperact Disord 2, 139-47 (2010).
Screening of human LPHN3 for variants with a potential impact on ADHD susceptibility.
Domené S, et al. Am J Med Genet B Neuropsychiatr Genet 156B, 11-8 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Peptidase_A17 (pfam05380)
  Pao retrotransposon peptidase.
7tm_2 (pfam00002)
  7 transmembrane receptor (Secretin family).
Gal_Lectin (pfam02140)
  Galactose binding lectin domain.
Latrophilin (pfam02354)
  Latrophilin Cytoplasmic C-terminal region.
DUF3497 (pfam12003)
  Domain of unknown function (DUF3497).
OLF (cl02549)
  Olfactomedin-like domain.
RT_like (cl02808)
  RT_like: Reverse transcriptase (RT, RNA-dependent DNA polymerase)_like family. An RT gene is usually indicative of a mobile element such as a retrotransposon or retrovirus. RTs occur in a variety of mobile elements, including retrotransposons, ...
Gal_Lectin (pfam02140)
  Galactose binding lectin domain.
Latrophilin (pfam02354)
  Latrophilin Cytoplasmic C-terminal region.
DUF3497 (pfam12003)
  Domain of unknown function (DUF3497).
HRM (cl02422)
  Hormone receptor domain.
OLF (cl02549)
  Olfactomedin-like domain.
GPS (cl02559)
  Latrophilin/CL-1-like GPS domain.
7tm_2 (cl19289)
  7 transmembrane receptor (Secretin family).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Lphn3 includes H.sapiens LPHN3 and R.norvegicus Lphn3.


 

 

 

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