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HomoloGene:22844. Gene conserved in Euteleostomi Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

CEP170,  H.sapiens
centrosomal protein 170kDa
1584 aa
CEP170,  P.troglodytes
centrosomal protein 170kDa
1584 aa
CEP170,  M.mulatta
centrosomal protein 170kDa
1584 aa
CEP170,  C.lupus
centrosomal protein 170kDa
1584 aa
CEP170,  B.taurus
centrosomal protein 170kDa
1585 aa
Cep170,  M.musculus
centrosomal protein 170
1578 aa
Cep170,  R.norvegicus
centrosomal protein 170
1566 aa
CEP170,  G.gallus
centrosomal protein 170kDa
1571 aa
LOC779465,  X.tropicalis
KARP-1-binding protein
1527 aa
cep170a,  D.rerio
centrosomal protein 170a
1486 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Global phosphoproteome of HT-29 human colon adenocarcinoma cells.
Kim JE, et al. J Proteome Res 4, 1339-46 (2005).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
CEP170_C (pfam15308)
  CEP170 C-terminus.
FHA (cl00062)
  Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cep170 includes H.sapiens CEP170.




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