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HomoloGene:136191. Gene conserved in Murinae Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

Macf1,  M.musculus
microtubule-actin crosslinking factor 1
NP_001186065.1
7355 aa
Macf1,  R.norvegicus
microtubule-actin crosslinking factor 1
NP_001129230.2
7351 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments





Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
GAS2 (cl02524)
  Growth-Arrest-Specific Protein 2 Domain.
Plectin (cl02531)
  Plectin repeat.
EFh (cd00051)
  EF-hand, calcium binding motif; A diverse superfamily of calcium sensors and calcium signal modulators; most examples in this alignment model have 2 active canonical EF hands. Ca2+ binding induces a conformational change in the EF-hand motif, leading to ...
SPEC (cd00176)
  Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
CH (cl00030)
  Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
Spectrin (cl02488)
  Spectrin repeat.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Macf1 includes H.sapiens MACF1.

 

 

 

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