Display Settings:

Format

Send to:

Choose Destination
HomoloGene:124481. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

PKD1L2,  H.sapiens
polycystic kidney disease 1-like 2
NP_443124.3
2459 aa
PKD1L2,  P.troglodytes
polycystic kidney disease 1-like 2
XP_511127.4
2467 aa
LOC717465,  M.mulatta
polycystic kidney disease protein 1-like 2-like
XP_002802618.1
2159 aa
PKD1L2,  C.lupus
polycystic kidney disease 1-like 2
XP_546816.3
2455 aa
PKD1L2,  B.taurus
polycystic kidney disease 1-like 2
XP_005218488.1
2407 aa
Pkd1l2,  M.musculus
polycystic kidney disease 1 like 2
NP_083962.4
2461 aa
LOC691069,  R.norvegicus
similar to polycystin 1-like 2
XP_006255764.1
2235 aa
LOC100858437,  G.gallus
polycystic kidney disease protein 1-like 2-like
XP_004944370.1
2441 aa
pkd1l2,  X.tropicalis
polycystic kidney disease 1-like 2
XP_002938183.2
2392 aa
im:7138475,  D.rerio
im:7138475
XP_002662959.2
1922 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Upregulation of PKD1L2 provokes a complex neuromuscular disease in the mouse.
Mackenzie FE, et al. Hum Mol Genet 18, 3553-66 (2009).
Polycystin-1L2 is a novel G-protein-binding protein.
Yuasa T, et al. Genomics 84, 126-38 (2004).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ion_trans (pfam00520)
  Ion transport protein.
GPS (pfam01825)
  Latrophilin/CL-1-like GPS domain.
REJ (pfam02010)
  REJ domain.
Gal_Lectin (pfam02140)
  Galactose binding lectin domain.
PKD_channel (pfam08016)
  Polycystin cation channel.
CLECT (cl02432)
  C-type lectin (CTL)/C-type lectin-like (CTLD) domain.
REJ (pfam02010)
  REJ domain.
Gal_Lectin (pfam02140)
  Galactose binding lectin domain.
PKD_channel (pfam08016)
  Polycystin cation channel.
PLAT (cl00011)
  PLAT (Polycystin-1, Lipoxygenase, Alpha-Toxin) domain or LH2 (Lipoxygenase homology 2) domain. It consists of an eight stranded beta-barrel. The domain can be found in various domain architectures, in case of lipoxygenases, alpha toxin, lipases and ...
CLECT (cl02432)
  C-type lectin (CTL)/C-type lectin-like (CTLD) domain.
GPS (cl02559)
  Latrophilin/CL-1-like GPS domain.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Pkd1l2 includes H.sapiens PKD1L2.


 

 

 

Support Center