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HomoloGene

Discover Homologs

HomoloGene:11864. Gene conserved in Eukaryota

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Genes Genes identified as putative homologs of one another during the construction of HomoloGene.			Proteins Proteins used in sequence comparisons and their conserved domain architectures.
	C16orf70, H.sapiens chromosome 16 open reading frame 70			NP_079463.2 422 aa
	C16H16orf70, P.troglodytes chromosome 16 open reading frame, human C16orf70			XP_511021.3 420 aa
	C20H16orf70, M.mulatta chromosome 16 open reading frame 70			XP_001086873.1 422 aa
	C5H16orf70, C.lupus chromosome 5 open reading frame, human C16orf70			XP_005620918.1 422 aa
	C18H16orf70, B.taurus chromosome 18 open reading frame, human C16orf70			NP_001098972.1 321 aa
	D230025D16Rik, M.musculus RIKEN cDNA D230025D16 gene			NP_663579.2 422 aa
	RGD621098, R.norvegicus similar to RIKEN cDNA D230025D16Rik			NP_620609.1 422 aa
	C11H16ORF70, G.gallus chromosome 11 open reading frame, human C16orf70			NP_001025736.1 423 aa
	LOC100494115, X.tropicalis chromosome unknown open reading frame, human C16orf70			XP_002937213.1 423 aa
	si:dkey-102f14.5, D.rerio si:dkey-102f14.5			NP_001076282.1 425 aa
	CG7083, D.melanogaster CG7083			NP_648211.1 438 aa
	AgaP_AGAP003820, A.gambiae AgaP_AGAP003820			XP_310381.3 461 aa
	T01G9.2, C.elegans T01G9.2			NP_492252.1 419 aa
	AT3G51130, A.thaliana AT3G51130			NP_566945.1 410 aa
	Os06g0714000, O.sativa Os06g0714000			NP_001058570.1 426 aa

Protein Alignments

Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST

Regenerate Alignments

Publications Articles associated with genes and sequences of this homology group.
Molecular cloning and characterization of rat lin-10. Ide N, et al. Biochem Biophys Res Commun 243, 634-8 (1998).
The PDZ domains of mLin-10 regulate its trans-Golgi network targeting and the surface expression of AMPA receptors. Stricker NL & Huganir RL. Neuropharmacology 45, 837-48 (2003).
Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila. McGurk L & Bonini NM. Hum Mol Genet 21, 76-84 (2012).
Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting. Borg JP, et al. J Biol Chem 273, 31633-6 (1998).
Kinesin superfamily motor protein KIF17 and mLin-10 in NMDA receptor-containing vesicle transport. Setou M, et al. Science 288, 1796-802 (2000).
Identification and investigation of Drosophila postsynaptic density homologs. Liebl FL & Featherstone DE. Bioinform Biol Insights 2, 369-81 (2008).
Urogenital and caudal dysgenesis in adrenocortical dysplasia (acd) mice is caused by a splicing mutation in a novel telomeric regulator. Keegan CE, et al. Hum Mol Genet 14, 113-23 (2005).

Conserved Domains Conserved Domains from CDD found in protein sequences by rpsblast searching.
UPF0183 (pfam03676) Uncharacterized protein family (UPF0183).
UPF0183 (pfam03676) Uncharacterized protein family (UPF0183).

Related Homology Resources Links to curated and computed homology information found in other databases.
MGI:2443049 Orthology group for M.musculus D230025D16Rik includes H.sapiens C16orf70 and R.norvegicus RGD621098.

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