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HomoloGene:11831. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

IFT74,  H.sapiens
intraflagellar transport 74 homolog (Chlamydomonas)
NP_079379.2
600 aa
IFT74,  P.troglodytes
intraflagellar transport 74 homolog (Chlamydomonas)
XP_001153797.1
600 aa
IFT74,  M.mulatta
intraflagellar transport 74 homolog (Chlamydomonas)
XP_002800122.1
600 aa
IFT74,  C.lupus
intraflagellar transport 74 homolog (Chlamydomonas)
XP_005626748.1
600 aa
IFT74,  B.taurus
intraflagellar transport 74 homolog (Chlamydomonas)
NP_001192704.1
600 aa
Ift74,  M.musculus
intraflagellar transport 74
NP_080595.2
600 aa
Ift74,  R.norvegicus
intraflagellar transport 74 homolog (Chlamydomonas)
NP_001007002.1
600 aa
IFT74,  G.gallus
intraflagellar transport 74 homolog (Chlamydomonas)
XP_003643118.1
591 aa
ift74,  X.tropicalis
intraflagellar transport 74 homolog
NP_001016062.1
601 aa
zgc:92052,  D.rerio
zgc:92052
NP_001002385.2
583 aa
AgaP_AGAP004724,  A.gambiae
AgaP_AGAP004724
XP_318104.4
623 aa
ift-74,  C.elegans
ift-74
NP_495359.1
674 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

IFT-81 and IFT-74 are required for intraflagellar transport in C. elegans.
Kobayashi T, et al. Genes Cells 12, 593-602 (2007).
Genetic studies of GRN and IFT74 in amyotrophic lateral sclerosis.
Xiao S, et al. Neurobiol Aging 29, 1279-82 (2008).
Primary cilia dynamics instruct tissue patterning and repair of corneal endothelium.
Blitzer AL, et al. Proc Natl Acad Sci U S A 108, 2819-24 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Smc (COG1196)
  Chromosome segregation ATPases [Cell division and chromosome partitioning].
SMC_prok_B (TIGR02168)
  chromosome segregation protein SMC, common bacterial type.
SMC_prok_A (TIGR02169)
  chromosome segregation protein SMC, primarily archaeal type.
SH3_and_anchor (TIGR04211)
  SH3 domain protein.
PRK03918 (PRK03918)
  chromosome segregation protein; Provisional.
Bap31 (cl02219)
  B-cell receptor-associated protein 31-like.
BAR (cl12013)
  The Bin/Amphiphysin/Rvs (BAR) domain, a dimerization module that binds membranes and detects membrane curvature.
DUF342 (cl19219)
  Protein of unknown function (DUF342).



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ift74 includes H.sapiens IFT74 and R.norvegicus Ift74.


 

 

 

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