Display Settings:

Format

Send to:

Choose Destination
HomoloGene:10804. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

UBR4,  H.sapiens
ubiquitin protein ligase E3 component n-recognin 4
NP_065816.2
5183 aa
UBR4,  P.troglodytes
ubiquitin protein ligase E3 component n-recognin 4
XP_513158.2
5183 aa
LOC702449,  M.mulatta
e3 ubiquitin-protein ligase UBR4-like
XP_002802257.1
5171 aa
UBR4,  C.lupus
ubiquitin protein ligase E3 component n-recognin 4
XP_005617954.1
5220 aa
UBR4,  B.taurus
ubiquitin protein ligase E3 component n-recognin 4
NP_001192721.1
5181 aa
Ubr4,  M.musculus
ubiquitin protein ligase E3 component n-recognin 4
NP_001153791.1
5180 aa
Ubr4,  R.norvegicus
ubiquitin protein ligase E3 component n-recognin 4
NP_001034115.1
5194 aa
UBR4,  G.gallus
ubiquitin protein ligase E3 component n-recognin 4
XP_417626.4
5076 aa
ubr4,  X.tropicalis
ubiquitin protein ligase E3 component n-recognin 4
XP_002943596.2
5147 aa
ubr4,  D.rerio
ubiquitin protein ligase E3 component n-recognin 4
XP_005162254.1
5178 aa
poe,  D.melanogaster
purity of essence
NP_001260222.1
5322 aa
AgaP_AGAP001157,  A.gambiae
AgaP_AGAP001157
XP_322005.5
5495 aa
C44E4.1,  C.elegans
C44E4.1
NP_740838.1
2710 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

p600 Plays Essential Roles in Fetal Development.
Nakaya T, et al. PLoS One 8, e66269 (2013).
p600, a unique protein required for membrane morphogenesis and cell survival.
Nakatani Y, et al. Proc Natl Acad Sci U S A 102, 15093-8 (2005).
The substrate recognition domains of the N-end rule pathway.
Tasaki T, et al. J Biol Chem 284, 1884-95 (2009).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
DZR (pfam12773)
  Double zinc ribbon.
E3_UbLigase_R4 (pfam13764)
  E3 ubiquitin-protein ligase UBR4.
PRK02967 (PRK02967)
  nickel responsive regulator; Provisional.
TNFR (cd00185)
  Tumor necrosis factor receptor (TNFR) domain; superfamily of TNF-like receptor domains. When bound to TNF-like cytokines, TNFRs trigger multiple signal transduction pathways, they are involved in inflammation response, apoptosis, autoimmunity and ...
DNA_PPF (pfam02916)
  DNA polymerase processivity factor.
DZR (pfam12773)
  Double zinc ribbon.
E3_UbLigase_R4 (pfam13764)
  E3 ubiquitin-protein ligase UBR4.
zf-UBR (cl19744)
  This region is found in E3 ubiquitin ligases that recognize N-recognins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ubr4 includes H.sapiens UBR4 and R.norvegicus Rbaf600.


 

 

 

Support Center