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HomoloGene:8215. Gene conserved in Euteleostomi

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Genes Genes identified as putative homologs of one another during the construction of HomoloGene.			Proteins Proteins used in sequence comparisons and their conserved domain architectures.
	BAMBI, H.sapiens BMP and activin membrane-bound inhibitor			NP_036474.1 260 aa
	BAMBI, P.troglodytes BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)			XP_001150397.2 330 aa
	BAMBI, M.mulatta BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)			XP_001106773.2 278 aa
	BAMBI, C.lupus BMP and activin membrane-bound inhibitor			XP_544209.1 260 aa
	BAMBI, B.taurus BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)			NP_001039774.1 260 aa
	Bambi, M.musculus BMP and activin membrane-bound inhibitor			NP_080781.1 260 aa
	Bambi, R.norvegicus BMP and activin membrane-bound inhibitor			NP_620782.1 260 aa
	BAMBI, G.gallus BMP and activin membrane-bound inhibitor homolog (Xenopus laevis)			NP_001182330.1 259 aa
	bambi, X.tropicalis BMP and activin membrane-bound inhibitor			NP_001008194.1 260 aa
	bambia, D.rerio BMP and activin membrane-bound inhibitor (Xenopus laevis) homolog a			NP_571859.1 258 aa

Protein Alignments

Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST

Regenerate Alignments

Publications Articles associated with genes and sequences of this homology group.
Accelerated reendothelialization, increased neovascularization and erythrocyte extravasation after arterial injury in BAMBI-/- mice. Guillot N, et al. PLoS One 8, e58550 (2013).
BAMBI regulates angiogenesis and endothelial homeostasis through modulation of alternative TGFβ signaling. Guillot N, et al. PLoS One 7, e39406 (2012).
Adiponectin induces the transforming growth factor decoy receptor BAMBI in human hepatocytes. Wanninger J, et al. FEBS Lett 585, 1338-44 (2011).
The TGF-beta-pseudoreceptor BAMBI is strongly expressed in COPD lungs and regulated by nontypeable Haemophilus influenzae. Drömann D, et al. Respir Res 11, 67 (2010).
BAMBI is overexpressed in ovarian cancer and co-translocates with Smads into the nucleus upon TGF-beta treatment. Pils D, et al. Gynecol Oncol 117, 189-97 (2010).
BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation. Tramullas M, et al. J Neurosci 30, 1502-11 (2010).
BAMBI gene is epigenetically silenced in subset of high-grade bladder cancer. Khin SS, et al. Int J Cancer 125, 328-38 (2009).
Cilia involvement in patterning and maintenance of the skeleton. Haycraft CJ & Serra R. Curr Top Dev Biol 85, 303-32 (2008).
Expression and regulation of the decoy bone morphogenetic protein receptor BAMBI in the developing avian face. Higashihori N, et al. Dev Dyn 237, 1500-8 (2008).
The TGF-beta pseudoreceptor gene Bambi is dispensable for mouse embryonic development and postnatal survival. Chen J, et al. Genesis 45, 482-6 (2007).
See all (50)

Conserved Domains Conserved Domains from CDD found in protein sequences by rpsblast searching.
BAMBI (pfam06211) BMP and activin membrane-bound inhibitor (BAMBI) N-terminal domain.

Related Homology Resources Links to curated and computed homology information found in other databases.
MGI:1915260 Orthology group for M.musculus Bambi includes H.sapiens BAMBI and R.norvegicus Bambi.

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