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HomoloGene:77068. Gene conserved in Bilateria Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

GIPC3,  H.sapiens
GIPC PDZ domain containing family, member 3
NP_573568.1
312 aa
GIPC3,  P.troglodytes
GIPC PDZ domain containing family, member 3
XP_001135295.1
305 aa
GIPC3,  M.mulatta
GIPC PDZ domain containing family, member 3
XP_001100669.1
312 aa
GIPC3,  C.lupus
GIPC PDZ domain containing family, member 3
XP_542175.2
316 aa
GIPC3,  B.taurus
GIPC PDZ domain containing family, member 3
NP_001193223.1
318 aa
Gipc3,  M.musculus
GIPC PDZ domain containing family, member 3
NP_683753.1
297 aa
Gipc3,  R.norvegicus
GIPC PDZ domain containing family, member 3
NP_001102752.1
297 aa
LOC100857667,  G.gallus
PDZ domain-containing protein GIPC3-like
XP_004948770.1
372 aa
gipc3,  X.tropicalis
GIPC PDZ domain containing family, member 3
NP_001096502.1
318 aa
zgc:136839,  D.rerio
zgc:136839
NP_001038783.1
333 aa
kermit,  D.melanogaster
kermit
NP_652028.1
336 aa
AgaP_AGAP007674,  A.gambiae
AgaP_AGAP007674
XP_001687864.1
342 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
???.



Publications
Articles associated with genes and sequences of this homology group.

Molecular cloning and characterization of mouse Gipc3.
Saitoh T, et al. Int J Mol Med 9, 251-6 (2002).
dGIPC is required for the locomotive activity and longevity in Drosophila.
Kim J, et al. Biochem Biophys Res Commun 402, 565-70 (2010).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PDZ (cl00117)
  PDZ domain, also called DHR (Dlg homologous region) or GLGF (after a conserved sequence motif). Many PDZ domains bind C-terminal polypeptides, though binding to internal (non-C-terminal) polypeptides and even to lipids has been demonstrated. ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Gipc3 includes H.sapiens GIPC3 and R.norvegicus Gipc3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Arthropoda
Insecta - insects (12 transcripts, 10 species)
Malacostraca - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Chordata
Mammalia - mammals (5 transcripts, 5 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (2 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (2 transcripts, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

 

 

 

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