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HomoloGene:75303. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

OSBP2,  H.sapiens
oxysterol binding protein 2
NP_110385.1
916 aa
OSBP2,  P.troglodytes
oxysterol binding protein 2
XP_003317247.1
750 aa
LOC716252,  M.mulatta
oxysterol-binding protein 2-like
XP_002808013.1
915 aa
OSBP2,  C.lupus
oxysterol binding protein 2
XP_005636508.1
920 aa
OSBP2,  B.taurus
oxysterol binding protein 2
NP_001179181.1
916 aa
Osbp2,  M.musculus
oxysterol binding protein 2
NP_690031.2
908 aa
Osbp2,  R.norvegicus
oxysterol binding protein 2
NP_001100702.1
896 aa
OSBP2,  G.gallus
oxysterol binding protein 2
XP_415293.4
800 aa
osbp2,  X.tropicalis
oxysterol binding protein 2
XP_002931752.2
808 aa
si:ch211-106a19.1,  D.rerio
si:ch211-106a19.1
NP_001116220.1
808 aa
Osbp,  D.melanogaster
Oxysterol binding protein
NP_477271.1
784 aa
AgaP_AGAP010893,  A.gambiae
AgaP_AGAP010893
XP_309799.4
778 aa
obr-1,  C.elegans
obr-1
NP_001255117.1
732 aa
ORP1C,  A.thaliana
ORP1C
NP_849343.2
813 aa
ORP1A,  A.thaliana
ORP1A
NP_180659.1
760 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

HLM/OSBP2 is expressed in chronic myeloid leukemia.
Henriques Silva N, et al. Int J Mol Med 12, 663-6 (2003).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PH_oxysterol_bp (cd01246)
  Oxysterol binding protein (OSBP) Pleckstrin homology (PH) domain.
Oxysterol_BP (pfam01237)
  Oxysterol-binding protein.
Oxysterol_BP (pfam01237)
  Oxysterol-binding protein.
PH-like (cl17171)
  Pleckstrin homology-like domain.
ApoLp-III_like (cl19113)
  Apolipophorin-III and similar insect proteins.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Osbp2 includes H.sapiens OSBP2 and R.norvegicus Osbp2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Streptophyta
Eudicotyledons - eudicots (46 transcripts, 29 species)
Liliopsida - monocots (27 transcripts, 9 species)
Coniferopsida - conifers (8 transcripts, 2 species)

Chordata
Actinopterygii - bony fishes (13 transcripts, 6 species)
Mammalia - mammals (10 transcripts, 9 species)
Ascidiacea - tunicates (3 transcripts, 1 species)
Amphibia - amphibians (2 transcripts, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (15 transcripts, 10 species)
Arachnida - arachnids (2 transcripts, 2 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Turbellaria - flatworms (5 transcripts, 1 species)
Trematoda - flatworms (4 transcripts, 2 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 2 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (3 transcripts, 2 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (2 transcripts, 1 species)

 

 

 

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