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HomoloGene:73902. Gene conserved in Boreoeutheria Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

CYP4F3,  H.sapiens
cytochrome P450, family 4, subfamily F, polypeptide 3
520 aa
LOC748117,  P.troglodytes
leukotriene-B(4) omega-hydroxylase 2-like
520 aa
LOC718349,  M.mulatta
leukotriene-B(4) omega-hydroxylase 1-like
520 aa
LOC484867,  C.lupus
leukotriene-B(4) omega-hydroxylase 2-like
520 aa
LOC534967,  B.taurus
leukotriene-B(4) omega-hydroxylase 2-like
522 aa
Cyp4f13,  M.musculus
cytochrome P450, family 4, subfamily f, polypeptide 13
523 aa
Cyp4f6,  R.norvegicus
cytochrome P450, family 4, subfamily f, polypeptide 6
537 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

Human cytochrome P450 4F3: structure, functions, and prospects.
Corcos L, et al. Drug Metabol Drug Interact 27, 63-71 (2012).
LTB4 can stimulate human osteoclast differentiation dependent of RANKL.
Chen ZK, et al. Artif Cells Blood Substit Immobil Biotechnol 38, 52-6 (2010).
Expression and physiological function of CYP4F subfamily in human eosinophils.
Kikuta Y, et al. Biochim Biophys Acta 1771, 1439-45 (2007).
Induction of cytochrome CYP4F3A in all-trans-retinoic acid-treated HL60 cells.
Mizukami Y, et al. Biochem Biophys Res Commun 314, 104-9 (2004).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
p450 (pfam00067)
  Cytochrome P450.
p450 (cl12078)
  Cytochrome P450.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Cyp4f13 includes H.sapiens CYP4F3 and R.norvegicus Cyp4f6.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (14 transcripts, 10 species)
Amphibia - amphibians (2 transcripts, 1 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Actinopterygii - bony fishes (1 transcript, 1 species)




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