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HomoloGene:55982. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MAN1A2,  H.sapiens
mannosidase, alpha, class 1A, member 2
NP_006690.1
641 aa
MAN1A2,  P.troglodytes
mannosidase, alpha, class 1A, member 2
XP_513685.2
641 aa
MAN1A2,  M.mulatta
mannosidase, alpha, class 1A, member 2
XP_001113249.1
641 aa
MAN1A2,  C.lupus
mannosidase, alpha, class 1A, member 2
XP_005630723.1
641 aa
MAN1A2,  B.taurus
mannosidase, alpha, class 1A, member 2
NP_001193806.1
641 aa
Man1a2,  M.musculus
mannosidase, alpha, class 1A, member 2
NP_034893.1
641 aa
Man1a2,  R.norvegicus
mannosidase, alpha, class 1A, member 2
NP_001099922.1
641 aa
MAN1A2,  G.gallus
mannosidase, alpha, class 1A, member 2
XP_416490.2
643 aa
man1a2,  X.tropicalis
mannosidase, alpha, class 1A, member 2
XP_002943491.1
643 aa
wu:fj20e02,  D.rerio
wu:fj20e02
NP_001243551.1
645 aa
alpha-Man-I,  D.melanogaster
alpha Mannosidase I
NP_996396.1
667 aa
AgaP_AGAP000558,  A.gambiae
AgaP_AGAP000558
XP_001688291.2
696 aa
C52E4.5,  C.elegans
C52E4.5
NP_001256388.1
636 aa
MGG_11475,  M.oryzae
MGG_11475
XP_003718084.1
1028 aa
NCU02235,  N.crassa
NCU02235
XP_959494.1
956 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

The architecture of parent-of-origin effects in mice.
Mott R, et al. Cell 156, 332-42 (2014).
The alpha-mannosidases: phylogeny and adaptive diversification.
Gonzalez DS & Jordan IK. Mol Biol Evol 17, 292-300 (2000).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AhaH (TIGR02926)
  ATP synthase archaeal, H subunit.
Glyco_hydro_47 (pfam01532)
  Glycosyl hydrolase family 47.
Glyco_hydro_47 (cl08327)
  Glycosyl hydrolase family 47.
Nop25 (pfam09805)
  Nucleolar protein 12 (25kDa).
Glyco_hydro_47 (cl08327)
  Glycosyl hydrolase family 47.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Man1a2 includes H.sapiens MAN1A2 and R.norvegicus Man1a2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (13 transcripts, 10 species)
Actinopterygii - bony fishes (6 transcripts, 5 species)
Amphibia - amphibians (3 transcripts, 2 species)
Ascidiacea - tunicates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)

Arthropoda
Insecta - insects (6 transcripts, 5 species)
Arachnida - arachnids (1 transcript, 1 species)
Branchiopoda - crustaceans (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (2 transcripts, 1 species)

Porifera
Demospongiae - sponges (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (1 transcript, 1 species)

 

 

 

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