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HomoloGene:542. Gene conserved in Opisthokonta Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

ABAT,  H.sapiens
4-aminobutyrate aminotransferase
NP_000654.2
500 aa
ABAT,  P.troglodytes
4-aminobutyrate aminotransferase
XP_001137090.1
500 aa
ABAT,  C.lupus
4-aminobutyrate aminotransferase
XP_005621619.1
500 aa
ABAT,  B.taurus
4-aminobutyrate aminotransferase
NP_001075050.1
500 aa
Abat,  M.musculus
4-aminobutyrate aminotransferase
NP_766549.2
500 aa
Abat,  R.norvegicus
4-aminobutyrate aminotransferase
NP_112265.1
500 aa
ABAT,  G.gallus
4-aminobutyrate aminotransferase
XP_004945379.1
500 aa
abat,  X.tropicalis
4-aminobutyrate aminotransferase
NP_001121529.1
500 aa
abat,  D.rerio
4-aminobutyrate aminotransferase
NP_958906.2
500 aa
CG7433,  D.melanogaster
CG7433
NP_001163479.1
486 aa
AgaP_AGAP006966,  A.gambiae
AgaP_AGAP006966
XP_308791.4
497 aa
gta-1,  C.elegans
gta-1
NP_501862.1
483 aa
UGA1,  S.cerevisiae
UGA1
NP_011533.3
471 aa
KLLA0F20548g,  K.lactis
KLLA0F20548g
XP_456003.1
472 aa
AGOS_AGL050C,  E.gossypii
AGOS_AGL050C
NP_986616.1
483 aa
uga1,  S.pombe
uga1
NP_594905.1
474 aa
MGG_01662,  M.oryzae
MGG_01662
XP_003714648.1
503 aa
NCU08998,  N.crassa
NCU08998
XP_959026.2
469 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
GABA-transaminase deficiency.



Publications
Articles associated with genes and sequences of this homology group.

GABA-transaminase, the liver and infantile autism.
Cohen BI. Med Hypotheses 57, 673-4 (2001).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
AAT_I (cl18945)
  Aspartate aminotransferase (AAT) superfamily (fold type I) of pyridoxal phosphate (PLP)-dependent enzymes. PLP combines with an alpha-amino acid to form a compound called a Schiff base or aldimine intermediate, which depending on the reaction, is the ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Abat includes H.sapiens ABAT and R.norvegicus Abat.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (13 transcripts, 9 species)
Mammalia - mammals (10 transcripts, 9 species)
Ascidiacea - tunicates (4 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (15 transcripts, 13 species)
Branchiopoda - crustaceans (3 transcripts, 1 species)
Arachnida - arachnids (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (3 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (2 transcripts, 2 species)

Porifera
Demospongiae - sponges (2 transcripts, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)
Hirudinida - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Platyhelminthes
Turbellaria - flatworms (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (8 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Basidiomycota
Heterobasidiomycetes - basidiomycetes (3 transcripts, 1 species)

Streptophyta
Coniferopsida - conifers (1 transcript, 1 species)

Oomycetes
Pythiales - oomycetes (1 transcript, 1 species)

Dictyosteliida
Dictyostelium - cellular slime molds (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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