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HomoloGene:44543. Gene conserved in Ecdysozoa

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Genes Genes identified as putative homologs of one another during the construction of HomoloGene.			Proteins Proteins used in sequence comparisons and their conserved domain architectures.
	7B2, D.melanogaster 7B2			NP_620471.3 271 aa
	AgaP_AGAP008082, A.gambiae AgaP_AGAP008082			XP_317375.3 248 aa
	sbt-1, C.elegans sbt-1			NP_508020.1 211 aa

Protein Alignments

Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST

Regenerate Alignments

Publications Articles associated with genes and sequences of this homology group.
Altered neuropeptide profile of Caenorhabditis elegans lacking the chaperone protein 7B2 as analyzed by mass spectrometry. Husson SJ & Schoofs L. FEBS Lett 581, 4288-92 (2007).
Cloning and functional analysis of C. elegans 7B2. Lindberg I, et al. DNA Cell Biol 17, 727-34 (1998).
Regulation of aging by unc-13 and sbt-1 in Caenorhabditis elegans is temperature-dependent. He KW, et al. Neurosci Bull 25, 335-42 (2009).
Interaction of Drosophila melanogaster prohormone convertase 2 and 7B2. Insect cell-specific processing and secretion. Hwang JR, et al. J Biol Chem 275, 17886-93 (2000).
Insect chitin synthase cDNA sequence, gene organization and expression. Tellam RL, et al. Eur J Biochem 267, 6025-43 (2000).
The Spn4 gene of Drosophila encodes a potent furin-directed secretory pathway serpin. Richer MJ, et al. Proc Natl Acad Sci U S A 101, 10560-5 (2004).
Analysis of the transcriptomes downstream of Eyeless and the Hedgehog, Decapentaplegic and Notch signaling pathways in Drosophila melanogaster. Nfonsam LE, et al. PLoS One 7, e44583 (2012).
Evolutionary dynamics of immune-related genes and pathways in disease-vector mosquitoes. Waterhouse RM, et al. Science 316, 1738-43 (2007).

Conserved Domains Conserved Domains from CDD found in protein sequences by rpsblast searching.
Secretogranin_V (pfam05281) Neuroendocrine protein 7B2 precursor (Secretogranin V).
Secretogranin_V (pfam05281) Neuroendocrine protein 7B2 precursor (Secretogranin V).

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