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HomoloGene:37744. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

TBCE,  H.sapiens
tubulin folding cofactor E
NP_001274730.1
578 aa
TBCE,  P.troglodytes
tubulin folding cofactor E
XP_003308872.1
578 aa
TBCE,  M.mulatta
tubulin folding cofactor E
XP_001100813.1
527 aa
TBCE,  C.lupus
tubulin folding cofactor E
XP_005618862.1
528 aa
TBCE,  B.taurus
tubulin folding cofactor E
NP_001033121.1
528 aa
Tbce,  M.musculus
tubulin-specific chaperone E
NP_848027.1
524 aa
Tbce,  R.norvegicus
tubulin folding cofactor E
NP_001012161.1
524 aa
TBCE,  G.gallus
tubulin folding cofactor E
XP_423980.3
529 aa
tbce,  X.tropicalis
tubulin folding cofactor E
NP_001016012.1
523 aa
tbce,  D.rerio
tubulin folding cofactor E
NP_001035078.2
521 aa
tbce,  D.melanogaster
tubulin-specific chaperone E
NP_610197.2
523 aa
AgaP_AGAP010770,  A.gambiae
AgaP_AGAP010770
XP_318537.3
520 aa
K07H8.1,  C.elegans
K07H8.1
NP_501395.1
493 aa
MGG_00378,  M.oryzae
MGG_00378
XP_003718699.1
616 aa
NCU09139,  N.crassa
NCU09139
XP_958911.1
584 aa
PFI,  A.thaliana
PFI
NP_565017.1
531 aa
Os05g0105300,  O.sativa
Os05g0105300
NP_001054410.1
179 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Hypoparathyroidism-retardation-dysmorphism syndrome.
Kenny-Caffey syndrome-1.



Publications
Articles associated with genes and sequences of this homology group.

Parathyroid development and the role of tubulin chaperone E.
Parvari R, et al. Horm Res 67, 12-21 (2007).
Characterization of neuromuscular transmission in mice with progressive motoneuronopathy.
Kretschmannová K & Zemková H. Physiol Res 53, 541-8 (2004).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Ribosomal_S21e (pfam01249)
  Ribosomal protein S21e.
LRR_4 (pfam12799)
  Leucine Rich repeats (2 copies).
LRR_8 (pfam13855)
  Leucine rich repeat.
LRR_RI (cd00116)
  Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
UBQ (cl00155)
  Ubiquitin-like proteins.
LRR_4 (pfam12799)
  Leucine Rich repeats (2 copies).
LRR_8 (pfam13855)
  Leucine rich repeat.
LRR_9 (pfam14580)
  Leucine-rich repeat.
UBQ (cl00155)
  Ubiquitin-like proteins.
CAP_GLY (cl08315)
  Cytoskeleton-associated proteins (CAPs) are involved in the organisation of microtubules and transportation of vesicles and organelles along the cytoskeletal network. A conserved motif, CAP-Gly, has been identified in a number of CAPs, including CLIP-170 and dynactins. The crystal structure of Caenorhabditis elegans F53F4.3 protein CAP-Gly domain was recently solved. The domain contains three beta-strands. The most conserved sequence, GKNDG, is located in two consecutive sharp turns on the surface, forming the entrance to a groove.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Tbce includes H.sapiens TBCE and R.norvegicus Tbce.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (15 transcripts, 14 species)
Actinopterygii - bony fishes (5 transcripts, 5 species)
Amniota - vertebrates (1 transcript, 1 species)
Aves - birds (1 transcript, 1 species)
Amphibia - amphibians (1 transcript, 1 species)

Arthropoda
Insecta - insects (10 transcripts, 8 species)
Branchiopoda - crustaceans (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 1 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (22 transcripts, 18 species)
Liliopsida - monocots (6 transcripts, 5 species)

Ascomycota
Sordariomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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