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HomoloGene:34271. Gene conserved in Diptera Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

Pink1,  D.melanogaster
PTEN-induced putative kinase 1
NP_727110.1
721 aa
AgaP_AGAP004315,  A.gambiae
AgaP_AGAP004315
XP_313587.5
674 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.

Loss of LRRK2/PARK8 induces degeneration of dopaminergic neurons in Drosophila.
Lee SB, et al. Biochem Biophys Res Commun 358, 534-9 (2007).
Antioxidants put Parkinson flies back in the PINK.
Bier E. Proc Natl Acad Sci U S A 103, 13269-70 (2006).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
PKc_like (cl09925)
  Protein Kinases, catalytic domain.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Arthropoda
Insecta - insects (11 transcripts, 7 species)

 

 

 

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