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HomoloGene:3325. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

MCM2,  H.sapiens
minichromosome maintenance complex component 2
NP_004517.2
904 aa
MCM2,  P.troglodytes
minichromosome maintenance complex component 2
XP_516724.2
904 aa
MCM2,  M.mulatta
minichromosome maintenance complex component 2
XP_001099580.2
901 aa
MCM2,  C.lupus
minichromosome maintenance complex component 2
XP_541736.3
919 aa
MCM2,  B.taurus
minichromosome maintenance complex component 2
XP_002707828.1
916 aa
Mcm2,  M.musculus
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
NP_032590.2
904 aa
Mcm2,  R.norvegicus
minichromosome maintenance complex component 2
NP_001101343.2
905 aa
MCM2,  G.gallus
minichromosome maintenance complex component 2
NP_001006139.1
888 aa
mcm2,  X.tropicalis
minichromosome maintenance complex component 2
NP_001006772.1
884 aa
mcm2,  D.rerio
MCM2 minichromosome maintenance deficient 2, mitotin (S. cerevisiae)
NP_775364.1
880 aa
Mcm2,  D.melanogaster
Minichromosome maintenance 2
NP_477121.1
887 aa
AgaP_AGAP004275,  A.gambiae
AgaP_AGAP004275
XP_313198.5
900 aa
mcm-2,  C.elegans
mcm-2
NP_001022416.1
881 aa
MCM2,  S.cerevisiae
MCM2
NP_009530.1
868 aa
KLLA0F12584g,  K.lactis
KLLA0F12584g
XP_455649.1
877 aa
AGOS_AFR178W,  E.gossypii
AGOS_AFR178W
NP_985725.1
885 aa
mcm2,  S.pombe
mcm2
NP_595477.1
830 aa
MGG_08122,  M.oryzae
MGG_08122
XP_003715082.1
873 aa
NCU04327,  N.crassa
NCU04327
XP_960973.1
882 aa
MCM2,  A.thaliana
MCM2
NP_175112.2
936 aa
Os11g0484300,  O.sativa
Os11g0484300
NP_001067910.1
961 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Publications
Articles associated with genes and sequences of this homology group.




Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
P-loop_NTPase (cl09099)
  P-loop containing Nucleoside Triphosphate Hydrolases.
MCM2_N (pfam12619)
  Mini-chromosome maintenance protein 2.
MCM2_N (pfam12619)
  Mini-chromosome maintenance protein 2.
MCM_N (pfam14551)
  MCM N-terminal domain.
AAA (cl18944)
  The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, ...



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Mcm2 includes H.sapiens MCM2 and R.norvegicus Mcm2.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (11 transcripts, 10 species)
Actinopterygii - bony fishes (11 transcripts, 8 species)
Aves - birds (3 transcripts, 3 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Amphibia - amphibians (2 transcripts, 2 species)
Amniota - vertebrates (1 transcript, 1 species)
Cephalochordata - lancelets (1 transcript, 1 species)
Hyperoartia - vertebrates (1 transcript, 1 species)

Arthropoda
Insecta - insects (8 transcripts, 7 species)
Arachnida - arachnids (2 transcripts, 2 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Platyhelminthes
Trematoda - flatworms (3 transcripts, 2 species)
Turbellaria - flatworms (1 transcript, 1 species)

Cnidaria
Hydrozoa - hydrozoans (2 transcripts, 2 species)
Anthozoa - anthozoans (1 transcript, 1 species)

Nematoda
Chromadorea - nematodes (3 transcripts, 2 species)

Echinodermata
Echinoidea - sea urchins (2 transcripts, 2 species)

Mollusca
Gastropoda - gastropods (1 transcript, 1 species)

Annelida
Hirudinida - segmented worms (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (26 transcripts, 21 species)
Liliopsida - monocots (11 transcripts, 9 species)
Coniferopsida - conifers (2 transcripts, 2 species)
Bryopsida - mosses (1 transcript, 1 species)

Chlorophyta
Chlorophyceae - green algae (1 transcript, 1 species)

Ascomycota
Sordariomycetes - ascomycetes (4 transcripts, 3 species)
Eurotiomycetes - ascomycetes (1 transcript, 1 species)
Pezizomycetes - ascomycetes (1 transcript, 1 species)

Ciliophora
Oligohymenophorea - ciliates (2 transcripts, 2 species)

Bacillariophyta
Bacillariophyceae - diatoms (1 transcript, 1 species)

Codonosigidae
Monosiga - choanoflagellates (1 transcript, 1 species)

 

 

 

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