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HomoloGene:2517. Gene conserved in Eukaryota Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

UCP3,  H.sapiens
uncoupling protein 3 (mitochondrial, proton carrier)
NP_003347.1
312 aa
UCP3,  P.troglodytes
uncoupling protein 3 (mitochondrial, proton carrier)
XP_001174875.1
312 aa
UCP3,  M.mulatta
uncoupling protein 3 (mitochondrial, proton carrier)
XP_001115599.1
312 aa
UCP3,  C.lupus
uncoupling protein 3 (mitochondrial, proton carrier)
NP_001003047.1
311 aa
UCP3,  B.taurus
uncoupling protein 3 (mitochondrial, proton carrier)
NP_776635.1
311 aa
Ucp3,  M.musculus
uncoupling protein 3 (mitochondrial, proton carrier)
NP_033490.1
308 aa
Ucp3,  R.norvegicus
uncoupling protein 3 (mitochondrial, proton carrier)
NP_037299.1
308 aa
UCP3,  G.gallus
uncoupling protein 3 (mitochondrial, proton carrier)
NP_989438.1
307 aa
ucp1,  X.tropicalis
uncoupling protein 1 (mitochondrial, proton carrier)
NP_001107354.1
309 aa
ucp1,  D.rerio
uncoupling protein 1
NP_955817.1
309 aa
UCP2,  A.thaliana
UCP2
NP_568894.1
305 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Obesity, severe, and type II diabetes.



Publications
Articles associated with genes and sequences of this homology group.

Role of uncoupling protein 3 in ischemia-reperfusion injury, arrhythmias, and preconditioning.
Ozcan C, et al. Am J Physiol Heart Circ Physiol 304, H1192-200 (2013).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Mito_carr (pfam00153)
  Mitochondrial carrier protein.
Mito_carr (pfam00153)
  Mitochondrial carrier protein.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Ucp3 includes H.sapiens UCP3 and R.norvegicus Ucp3.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Actinopterygii - bony fishes (14 transcripts, 11 species)
Mammalia - mammals (11 transcripts, 10 species)
Amphibia - amphibians (4 transcripts, 2 species)
Ascidiacea - tunicates (2 transcripts, 2 species)
Aves - birds (2 transcripts, 2 species)
Cephalochordata - lancelets (1 transcript, 1 species)

Arthropoda
Insecta - insects (1 transcript, 1 species)
Maxillopoda - crustaceans (1 transcript, 1 species)

Cnidaria
Anthozoa - anthozoans (1 transcript, 1 species)

Annelida
Polychaeta - segmented worms (1 transcript, 1 species)

Echinodermata
Echinoidea - sea urchins (1 transcript, 1 species)

Streptophyta
Eudicotyledons - eudicots (28 transcripts, 21 species)
Liliopsida - monocots (3 transcripts, 3 species)

 

 

 

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