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HomoloGene:21002. Gene conserved in Tetrapoda Download , Links
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins used in sequence comparisons and their conserved domain architectures.

MED1,  H.sapiens
mediator complex subunit 1
1581 aa
MED1,  P.troglodytes
mediator complex subunit 1
1581 aa
MED1,  C.lupus
mediator complex subunit 1
1583 aa
MED1,  B.taurus
mediator complex subunit 1
1575 aa
Med1,  M.musculus
mediator complex subunit 1
1575 aa
Med1,  R.norvegicus
mediator complex subunit 1
1567 aa
MED1,  G.gallus
mediator complex subunit 1
1583 aa
med1,  X.tropicalis
mediator of RNA polymerase II transcription subunit 1
1573 aa

Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments

Articles associated with genes and sequences of this homology group.

[Hyperlipidemia in hepatic MED1 deficient mice in response to fasting].
Bai L, et al. Sheng Wu Gong Cheng Xue Bao 27, 1490-8 (2011).
Essential role of Mediator subunit Med1 in invariant natural killer T-cell development.
Yue X, et al. Proc Natl Acad Sci U S A 108, 17105-10 (2011).

Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
Med1 (pfam10744)
  Mediator of RNA polymerase II transcription subunit 1.
Med1 (pfam10744)
  Mediator of RNA polymerase II transcription subunit 1.

Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Med1 includes H.sapiens MED1 and R.norvegicus Med1.

Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Mammalia - mammals (18 transcripts, 14 species)
Actinopterygii - bony fishes (4 transcripts, 3 species)
Amphibia - amphibians (3 transcripts, 2 species)
Aves - birds (2 transcripts, 1 species)
Amniota - vertebrates (1 transcript, 1 species)

Insecta - insects (2 transcripts, 2 species)




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