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HomoloGene:20216. Gene conserved in Euteleostomi Download , Links
Genes
Genes identified as putative homologs of one another during the construction of HomoloGene.

Proteins
Proteins used in sequence comparisons and their conserved domain architectures.

DRD5,  H.sapiens
dopamine receptor D5
NP_000789.1
477 aa
DRD5,  P.troglodytes
dopamine receptor D5
XP_528711.2
477 aa
DRD5,  M.mulatta
dopamine receptor D5
XP_001097117.1
478 aa
DRD5,  C.lupus
dopamine receptor D5
XP_005618635.1
474 aa
DRD5,  B.taurus
dopamine receptor D5
NP_001193558.1
473 aa
Drd5,  M.musculus
dopamine receptor D5
NP_038531.1
478 aa
Drd5,  R.norvegicus
dopamine receptor D5
NP_036900.1
475 aa
SPATA2L,  G.gallus
spermatogenesis associated 2-like
XP_004936358.1
478 aa
LOC100495174,  X.tropicalis
D(1B) dopamine receptor-like
XP_004911296.1
455 aa
drd7,  D.rerio
dopamine receptor D7
NP_001107115.1
443 aa


Protein Alignments
Protein multiple alignment, pairwise similarity scores and evolutionary distances.

Show Multiple Alignment

Show Pairwise Alignment Scores

Pairwise alignments generated using BLAST
Regenerate Alignments




Phenotypes
Phenotypic information for the genes in this entry imported from model organism databases.

H.sapiens
Dystonia, primary cervical.
Attention deficit-hyperactivity disorder, susceptibility to.
Blepharospasm, primary benign.



Publications
Articles associated with genes and sequences of this homology group.

Trafficking properties of the D5 dopamine receptor.
Thompson D & Whistler JL. Traffic 12, 644-56 (2011).
Lack of renal dopamine D5 receptors promotes hypertension.
Asico L, et al. J Am Soc Nephrol 22, 82-9 (2011).



Conserved Domains
Conserved Domains from CDD found in protein sequences by rpsblast searching.
7tm_4 (cl10458)
  Olfactory receptor.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7TM_GPCR_Srx (pfam10328)
  Serpentine type 7TM GPCR chemoreceptor Srx.
7tm_1 (pfam00001)
  7 transmembrane receptor (rhodopsin family).
7TM_GPCR_Srx (pfam10328)
  Serpentine type 7TM GPCR chemoreceptor Srx.



Related Homology Resources
Links to curated and computed homology information found in other databases.
Orthology group for M.musculus Drd5 includes H.sapiens DRD5 and R.norvegicus Drd5.



UniGene
Links to UniGene entries found by comparing the homologous proteins against the transcript database.

Chordata
Mammalia - mammals (7 transcripts, 7 species)
Aves - birds (4 transcripts, 2 species)
Actinopterygii - bony fishes (2 transcripts, 2 species)
Amphibia - amphibians (1 transcript, 1 species)

 

 

 

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